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1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/meta-substituted arenes.

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Bibliographic Details
Title: 1,2-Difunctionalized bicyclo[1.1.1]pentanes: Long-sought-after mimetics for ortho/meta-substituted arenes.
Authors: Zhao JX; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037.; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, People's Republic of China., Chang YX; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., He C; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Burke BJ; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Collins MR; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121; michael.collins@pfizer.com pbaran@scripps.edu., Del Bel M; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Elleraas J; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Gallego GM; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Montgomery TP; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Mousseau JJ; Discovery Sciences, Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT 06340., Nair SK; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Perry MA; Discovery Sciences, Medicine Design, Pfizer Worldwide Research, Development and Medical, Groton, CT 06340., Spangler JE; Oncology Medicinal Chemistry, Pfizer Worldwide Research, Development and Medical, San Diego, CA 92121., Vantourout JC; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037., Baran PS; Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037; michael.collins@pfizer.com pbaran@scripps.edu.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Jul 13; Vol. 118 (28).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2108881118