The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3).
Saved in:
| Title: | The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). |
|---|---|
| Authors: | Berthelet J; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Michail C; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Bui LC; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Le Coadou L; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Sirri V; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Wang L; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Dulphy N; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Dupret JM; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Chomienne C; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Guidez F; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.)., Rodrigues-Lima F; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.) fernando.rodrigues-lima@univ-paris-diderot. |
| Source: | Molecular pharmacology [Mol Pharmacol] 2021 Sep; Vol. 100 (3), pp. 283-294. Date of Electronic Publication: 2021 Jul 15. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34266924 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Berthelet+J%22">Berthelet J</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Michail+C%22">Michail C</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Bui+LC%22">Bui LC</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Le+Coadou+L%22">Le Coadou L</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Sirri+V%22">Sirri V</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Dulphy+N%22">Dulphy N</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Dupret+JM%22">Dupret JM</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Chomienne+C%22">Chomienne C</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Guidez+F%22">Guidez F</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.).<br /><searchLink fieldCode="AU" term="%22Rodrigues-Lima+F%22">Rodrigues-Lima F</searchLink>; Université de Paris, Unité de Biologie Fonctionnelle et Adaptative (BFA), UMR 8251, CNRS, Paris, France (J.B., C.M., L.-C.B., L.L.C., V.S., J.-M.D., F.R.-L.); The First Affiliated Hospital of Chongqing Medical University, Department of Hematology, Chongqing, China (L.W.); Université de Paris, Institut de Recherche Saint-Louis (IRSL), UMRS 1160 (N.D.), UMRS 1131 (C.C., F.G.), INSERM, Paris, France; and Service de Biologie Cellulaire, Assistance Publique des Hôpitaux de Paris (AP-HP), Hôpital Saint Louis, Paris, France (C.C.) fernando.rodrigues-lima@univ-paris-diderot. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220035623%22">Molecular pharmacology</searchLink> [Mol Pharmacol] 2021 Sep; Vol. 100 (3), pp. 283-294. <i>Date of Electronic Publication: </i>2021 Jul 15. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>0035623 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1521-0111 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220026895X%22">0026895X </searchLink><i>NLM ISO Abbreviation: </i>Mol Pharmacol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34266924 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1124/molpharm.121.000303 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 283 Titles: – TitleFull: The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3). Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Berthelet J – PersonEntity: Name: NameFull: Michail C – PersonEntity: Name: NameFull: Bui LC – PersonEntity: Name: NameFull: Le Coadou L – PersonEntity: Name: NameFull: Sirri V – PersonEntity: Name: NameFull: Wang L – PersonEntity: Name: NameFull: Dulphy N – PersonEntity: Name: NameFull: Dupret JM – PersonEntity: Name: NameFull: Chomienne C – PersonEntity: Name: NameFull: Guidez F – PersonEntity: Name: NameFull: Rodrigues-Lima F IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2021 Sep Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1521-0111 Numbering: – Type: volume Value: 100 – Type: issue Value: 3 Titles: – TitleFull: Molecular pharmacology Type: main |
| ResultId | 1 |
