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3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.

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Title: 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.
Authors: Clement CC; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA., D'Alessandro A; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Thangaswamy S; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA., Chalmers S; Division of Rheumatology and the Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Furtado R; Division of Rheumatology and the Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Spada S; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA., Mondanelli G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Ianni F; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Gehrke S; Department of Biochemistry and Molecular Genetics, University of Colorado Denver, Anschutz Medical Campus, Aurora, CO, USA., Gargaro M; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Manni G; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Cara LCL; Department of Pharmaceutical & Organic Chemistry, Faculty of Pharmacy, University of Granada, Granada, Spain., Runge P; Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland., Tsai WL; Translational Immunology Section, National Institute of Arthritis Musculoskeletal and Skin Diseases, Bethesda, MD, USA., Karaman S; Wihuri Research Institute and Translational Cancer Medicine Research Program, University of Helsinki, Helsinki, Finland., Arasa J; Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland., Fernandez-Rodriguez R; Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Beck A; Department of Pathology, Albert Einstein College of Medicine, New York, NY, USA., Macchiarulo A; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Gadina M; Translational Immunology Section, National Institute of Arthritis Musculoskeletal and Skin Diseases, Bethesda, MD, USA., Halin C; Institute of Pharmaceutical Sciences, ETH Zurich, Zurich, Switzerland., Fallarino F; Department of Medicine and Surgery, University of Perugia, Perugia, Italy., Skobe M; Department of Oncological Sciences and Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Veldhoen M; Instituto de Medicina Molecular João Lobo Antunes, Faculdade de Medicina da Universidade de Lisboa, Lisbon, Portugal., Moretti S; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche 'Togo Rosati', Perugia, Italy., Formenti S; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, New York, NY, USA., Demaria S; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA.; Sandra and Edward Meyer Cancer Center, New York, NY, USA., Soni RK; Proteomics and Macromolecular Crystallography Shared Resource, Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, NY, USA., Galarini R; Istituto Zooprofilattico Sperimentale dell'Umbria e delle Marche 'Togo Rosati', Perugia, Italy., Sardella R; Department of Pharmaceutical Sciences, University of Perugia, Perugia, Italy., Lauvau G; Division of Rheumatology and the Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA., Putterman C; Division of Rheumatology and the Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, NY, USA.; Azrieli Faculty of Medicine, Bar-Ilan University, Zefat, Israel.; Research Institute, Galilee Medical Center, Nahariya, Israel., Alitalo K; Wihuri Research Institute and Translational Cancer Medicine Research Program, University of Helsinki, Helsinki, Finland., Grohmann U; Department of Medicine and Surgery, University of Perugia, Perugia, Italy. ursula.grohmann@unipg.it.; Department of Pathology, Albert Einstein College of Medicine, New York, NY, USA. ursula.grohmann@unipg.it., Santambrogio L; Department of Radiation Oncology, Weill Cornell Medicine, New York, NY, USA. las4011@med.cornell.edu.; Department of Pathology, Albert Einstein College of Medicine, New York, NY, USA. las4011@med.cornell.edu.; Sandra and Edward Meyer Cancer Center, New York, NY, USA. las4011@med.cornell.edu.; Caryl and Israel Englander Institute for Precision Medicine of Weill Cornell Medicine, New York, NY, USA. las4011@med.cornell.edu.
Source: Nature communications [Nat Commun] 2021 Jul 21; Vol. 12 (1), pp. 4447. Date of Electronic Publication: 2021 Jul 21.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: 3-hydroxy-L-kynurenamine is an immunomodulatory biogenic amine.
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