O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics.
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| Title: | O-Linked-N-Acetylglucosaminylation of the RNA-Binding Protein EWS N-Terminal Low Complexity Region Reduces Phase Separation and Enhances Condensate Dynamics. |
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| Authors: | Nosella ML; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Tereshchenko M; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Pritišanac I; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Chong PA; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada., Toretsky JA; Departments of Oncology and Pediatrics, Georgetown University, Washington, D.C. 20057, United States., Lee HO; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada., Forman-Kay JD; Molecular Medicine Program, The Hospital for Sick Children, Toronto, ON M5G 0A4, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON M5S 1A8, Canada. |
| Source: | Journal of the American Chemical Society [J Am Chem Soc] 2021 Aug 04; Vol. 143 (30), pp. 11520-11534. Date of Electronic Publication: 2021 Jul 25. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1520-5126 |
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| DOI: | 10.1021/jacs.1c04194 |
