Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial.
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| Title: | Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial. |
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| Authors: | Delgado-Enciso I; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Paz-Garcia J; Department of Internal Medicine and Surgery, Union Hospital Center, Villa de Álvarez, Colima 28970, México., Barajas-Saucedo CE; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Mokay-Ramírez KA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Meza-Robles C; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Lopez-Flores R; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Delgado-Machuca M; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Murillo-Zamora E; Department of Research, General Hospital of Zone No. 1 and Family Medicine Unit No. 19 IMSS, Villa de Alvarez, Colima 28984, México., Toscano-Velazquez JA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Delgado-Enciso J; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México., Melnikov V; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Walle-Guillen M; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Galvan-Salazar HR; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Delgado-Enciso OG; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México., Cabrera-Licona A; Department of Research, Esteripharma S.A. de C.V., Ciudad de México 03100, México., Danielewicz-Mata EJ; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Mandujano-Diaz PJ; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Guzman-Esquivel J; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México., Montes-Galindo DA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Perez-Martinez H; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Jimenez-Villegaz JM; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Hernandez-Rangel AE; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Montes-Diaz P; Private Medical Office Xochitepec, Xochitepec, Morelos 62795, México., Rodriguez-Sanchez IP; Laboratory of Molecular and Structural Physiology, School of Biological Sciences, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo León 66455, México., Martinez-Fierro ML; Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, México., Garza-Veloz I; Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, México., Tiburcio-Jimenez D; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Zaizar-Fregoso SA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Gonzalez-Alcaraz F; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Gutierrez-Gutierrez L; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Diaz-Lopez L; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México., Ramirez-Flores M; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Guzman-Solorzano HP; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Gaytan-Sandoval G; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Martinez-Perez CR; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Espinoza-Gómez F; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Rojas-Larios F; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Hirsch-Meillon MJ; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Baltazar-Rodriguez LM; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Barrios-Navarro E; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Oviedo-Rodriguez V; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México., Mendoza-Hernandez MA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Prieto-Diaz-Chavez E; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México., Paz-Michel BA; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Esteripharma S.A. de C.V., Ciudad de México 03100, México. |
| Source: | Experimental and therapeutic medicine [Exp Ther Med] 2021 Sep; Vol. 22 (3), pp. 915. Date of Electronic Publication: 2021 Jun 29. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Spandidos Pub.] Country of Publication: Greece NLM ID: 101531947 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1792-1015 (Electronic) Linking ISSN: 17920981 NLM ISO Abbreviation: Exp Ther Med Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34306189 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Delgado-Enciso+I%22">Delgado-Enciso I</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Paz-Garcia+J%22">Paz-Garcia J</searchLink>; Department of Internal Medicine and Surgery, Union Hospital Center, Villa de Álvarez, Colima 28970, México.<br /><searchLink fieldCode="AU" term="%22Barajas-Saucedo+CE%22">Barajas-Saucedo CE</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Mokay-Ramírez+KA%22">Mokay-Ramírez KA</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Meza-Robles+C%22">Meza-Robles C</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Lopez-Flores+R%22">Lopez-Flores R</searchLink>; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Delgado-Machuca+M%22">Delgado-Machuca M</searchLink>; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Murillo-Zamora+E%22">Murillo-Zamora E</searchLink>; Department of Research, General Hospital of Zone No. 1 and Family Medicine Unit No. 19 IMSS, Villa de Alvarez, Colima 28984, México.<br /><searchLink fieldCode="AU" term="%22Toscano-Velazquez+JA%22">Toscano-Velazquez JA</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Delgado-Enciso+J%22">Delgado-Enciso J</searchLink>; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Melnikov+V%22">Melnikov V</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Walle-Guillen+M%22">Walle-Guillen M</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Galvan-Salazar+HR%22">Galvan-Salazar HR</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Delgado-Enciso+OG%22">Delgado-Enciso OG</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Cabrera-Licona+A%22">Cabrera-Licona A</searchLink>; Department of Research, Esteripharma S.A. de C.V., Ciudad de México 03100, México.<br /><searchLink fieldCode="AU" term="%22Danielewicz-Mata+EJ%22">Danielewicz-Mata EJ</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Mandujano-Diaz+PJ%22">Mandujano-Diaz PJ</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Guzman-Esquivel+J%22">Guzman-Esquivel J</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Foundation for Cancer Ethics, Education and Research of the Cancerology State Institute, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Montes-Galindo+DA%22">Montes-Galindo DA</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Perez-Martinez+H%22">Perez-Martinez H</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Jimenez-Villegaz+JM%22">Jimenez-Villegaz JM</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Hernandez-Rangel+AE%22">Hernandez-Rangel AE</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Montes-Diaz+P%22">Montes-Diaz P</searchLink>; Private Medical Office Xochitepec, Xochitepec, Morelos 62795, México.<br /><searchLink fieldCode="AU" term="%22Rodriguez-Sanchez+IP%22">Rodriguez-Sanchez IP</searchLink>; Laboratory of Molecular and Structural Physiology, School of Biological Sciences, Universidad Autónoma de Nuevo León, San Nicolas de los Garza, Nuevo León 66455, México.<br /><searchLink fieldCode="AU" term="%22Martinez-Fierro+ML%22">Martinez-Fierro ML</searchLink>; Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, México.<br /><searchLink fieldCode="AU" term="%22Garza-Veloz+I%22">Garza-Veloz I</searchLink>; Molecular Medicine Laboratory, Academic Unit of Human Medicine and Health Sciences, Autonomous University of Zacatecas, Zacatecas 98160, México.<br /><searchLink fieldCode="AU" term="%22Tiburcio-Jimenez+D%22">Tiburcio-Jimenez D</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Zaizar-Fregoso+SA%22">Zaizar-Fregoso SA</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Gonzalez-Alcaraz+F%22">Gonzalez-Alcaraz F</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Gutierrez-Gutierrez+L%22">Gutierrez-Gutierrez L</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Diaz-Lopez+L%22">Diaz-Lopez L</searchLink>; COVID-19 Respiratory Care Clinic INSABI Poliforum, Tuxtla Gutierrez, Chiapas 29040, México.<br /><searchLink fieldCode="AU" term="%22Ramirez-Flores+M%22">Ramirez-Flores M</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Guzman-Solorzano+HP%22">Guzman-Solorzano HP</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Gaytan-Sandoval+G%22">Gaytan-Sandoval G</searchLink>; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Martinez-Perez+CR%22">Martinez-Perez CR</searchLink>; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Espinoza-Gómez+F%22">Espinoza-Gómez F</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Rojas-Larios+F%22">Rojas-Larios F</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Hirsch-Meillon+MJ%22">Hirsch-Meillon MJ</searchLink>; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Baltazar-Rodriguez+LM%22">Baltazar-Rodriguez LM</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Barrios-Navarro+E%22">Barrios-Navarro E</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Oviedo-Rodriguez+V%22">Oviedo-Rodriguez V</searchLink>; Department of Research, Cancerology State Institute, Colima State Health Services, Colima 28085, México.<br /><searchLink fieldCode="AU" term="%22Mendoza-Hernandez+MA%22">Mendoza-Hernandez MA</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Prieto-Diaz-Chavez+E%22">Prieto-Diaz-Chavez E</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.<br /><searchLink fieldCode="AU" term="%22Paz-Michel+BA%22">Paz-Michel BA</searchLink>; Department of Molecular Medicine, School of Medicine, University of Colima, Colima 28040, México.; Department of Research, Esteripharma S.A. de C.V., Ciudad de México 03100, México. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101531947%22">Experimental and therapeutic medicine</searchLink> [Exp Ther Med] 2021 Sep; Vol. 22 (3), pp. 915. <i>Date of Electronic Publication: </i>2021 Jun 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Spandidos+Pub%2E]%22">Spandidos Pub.] </searchLink><i>Country of Publication: </i>Greece <i>NLM ID: </i>101531947 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1792-1015 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217920981%22">17920981 </searchLink><i>NLM ISO Abbreviation: </i>Exp Ther Med <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34306189 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3892/etm.2021.10347 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 915 Titles: – TitleFull: Safety and efficacy of a COVID-19 treatment with nebulized and/or intravenous neutral electrolyzed saline combined with usual medical care vs. usual medical care alone: A randomized, open-label, controlled trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Delgado-Enciso I – PersonEntity: Name: NameFull: Paz-Garcia J – PersonEntity: Name: NameFull: Barajas-Saucedo CE – PersonEntity: Name: NameFull: Mokay-Ramírez KA – PersonEntity: Name: NameFull: Meza-Robles C – PersonEntity: Name: NameFull: Lopez-Flores R – PersonEntity: Name: NameFull: Delgado-Machuca M – PersonEntity: Name: NameFull: Murillo-Zamora E – PersonEntity: Name: NameFull: Toscano-Velazquez JA – PersonEntity: Name: NameFull: Delgado-Enciso J – PersonEntity: Name: NameFull: Melnikov V – PersonEntity: Name: NameFull: Walle-Guillen M – PersonEntity: Name: NameFull: Galvan-Salazar HR – PersonEntity: Name: NameFull: Delgado-Enciso OG – PersonEntity: Name: NameFull: Cabrera-Licona A – PersonEntity: Name: NameFull: Danielewicz-Mata EJ – PersonEntity: Name: NameFull: Mandujano-Diaz PJ – PersonEntity: Name: NameFull: Guzman-Esquivel J – PersonEntity: Name: NameFull: Montes-Galindo DA – PersonEntity: Name: NameFull: Perez-Martinez H – PersonEntity: Name: NameFull: Jimenez-Villegaz JM – PersonEntity: Name: NameFull: Hernandez-Rangel AE – PersonEntity: Name: NameFull: Montes-Diaz P – PersonEntity: Name: NameFull: Rodriguez-Sanchez IP – PersonEntity: Name: NameFull: Martinez-Fierro ML – PersonEntity: Name: NameFull: Garza-Veloz I – PersonEntity: Name: NameFull: Tiburcio-Jimenez D – PersonEntity: Name: NameFull: Zaizar-Fregoso SA – PersonEntity: Name: NameFull: Gonzalez-Alcaraz F – PersonEntity: Name: NameFull: Gutierrez-Gutierrez L – PersonEntity: Name: NameFull: Diaz-Lopez L – PersonEntity: Name: NameFull: Ramirez-Flores M – PersonEntity: Name: NameFull: Guzman-Solorzano HP – PersonEntity: Name: NameFull: Gaytan-Sandoval G – PersonEntity: Name: NameFull: Martinez-Perez CR – PersonEntity: Name: NameFull: Espinoza-Gómez F – PersonEntity: Name: NameFull: Rojas-Larios F – PersonEntity: Name: NameFull: Hirsch-Meillon MJ – PersonEntity: Name: NameFull: Baltazar-Rodriguez LM – PersonEntity: Name: NameFull: Barrios-Navarro E – PersonEntity: Name: NameFull: Oviedo-Rodriguez V – PersonEntity: Name: NameFull: Mendoza-Hernandez MA – PersonEntity: Name: NameFull: Prieto-Diaz-Chavez E – PersonEntity: Name: NameFull: Paz-Michel BA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 2021 Sep Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1792-1015 Numbering: – Type: volume Value: 22 – Type: issue Value: 3 Titles: – TitleFull: Experimental and therapeutic medicine Type: main |
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