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Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.

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Title: Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
Authors: Rücker FG; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany., Du L; Novartis Pharmaceuticals, Cambridge, MA, USA., Luck TJ; Department of Hematology, Oncology and Tumor Immunology, Charité University, Berlin, Germany., Benner A; Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany., Krzykalla J; Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany., Gathmann I; Novartis Pharmaceuticals, Basel, Switzerland., Voso MT; Department of Biomedicine and Prevention, Università di Roma 'Tor Vergata', Rome, Italy., Amadori S; Department of Biomedicine and Prevention, Università di Roma 'Tor Vergata', Rome, Italy., Prior TW; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Brandwein JM; Department of Medicine, University of Alberta, Edmonton, AB, Canada., Appelbaum FR; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Medeiros BC; Division of Hematology, Stanford Comprehensive Cancer Center, Stanford University, Stanford, CA, USA., Tallman MS; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA., Savoie L; University of Calgary, Calgary, AB, Canada., Sierra J; Hematology Department, Hospital de la Santa Creu i Sant Pau and Jose Carreras Leukemia Research Institute, Autonomus University of Barcelona, Barcelona, Spain., Pallaud C; Novartis Pharmaceuticals, Basel, Switzerland., Sanz MA; Hospital Universitario la Fe, Hematology Department, Department of Medicine, University of Valencia, Valencia, Spain., Jansen JH; Radboud Institute Molecular Studies, Radboud University Medical Center, Nijmegen, The Netherlands., Niederwieser D; Hematology and Oncology, University of Leipzig, Leipzig, Germany., Fischer T; Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany., Ehninger G; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden, Germany., Heuser M; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Ganser A; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany., Bullinger L; Department of Hematology, Oncology and Tumor Immunology, Charité University, Berlin, Germany., Larson RA; Department of Medicine and Comprehensive Cancer Center, University of Chicago, Chicago, IL, USA., Bloomfield CD; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA., Stone RM; Department of Medical Oncology, Dana-Farber/Partners CancerCare, Boston, MA, USA., Döhner H; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany., Thiede C; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden, Germany., Döhner K; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany. konstanze.doehner@uniklinik-ulm.de.
Source: Leukemia [Leukemia] 2022 Jan; Vol. 36 (1), pp. 90-99. Date of Electronic Publication: 2021 Jul 28.
Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE
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  Data: Molecular landscape and prognostic impact of FLT3-ITD insertion site in acute myeloid leukemia: RATIFY study results.
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  Data: <searchLink fieldCode="AU" term="%22Rücker+FG%22">Rücker FG</searchLink>; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Du+L%22">Du L</searchLink>; Novartis Pharmaceuticals, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Luck+TJ%22">Luck TJ</searchLink>; Department of Hematology, Oncology and Tumor Immunology, Charité University, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Benner+A%22">Benner A</searchLink>; Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Krzykalla+J%22">Krzykalla J</searchLink>; Division of Biostatistics, German Cancer Research Center, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Gathmann+I%22">Gathmann I</searchLink>; Novartis Pharmaceuticals, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Voso+MT%22">Voso MT</searchLink>; Department of Biomedicine and Prevention, Università di Roma 'Tor Vergata', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Amadori+S%22">Amadori S</searchLink>; Department of Biomedicine and Prevention, Università di Roma 'Tor Vergata', Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Prior+TW%22">Prior TW</searchLink>; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Brandwein+JM%22">Brandwein JM</searchLink>; Department of Medicine, University of Alberta, Edmonton, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Appelbaum+FR%22">Appelbaum FR</searchLink>; Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Medeiros+BC%22">Medeiros BC</searchLink>; Division of Hematology, Stanford Comprehensive Cancer Center, Stanford University, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Tallman+MS%22">Tallman MS</searchLink>; Leukemia Service, Department of Medicine, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Savoie+L%22">Savoie L</searchLink>; University of Calgary, Calgary, AB, Canada.<br /><searchLink fieldCode="AU" term="%22Sierra+J%22">Sierra J</searchLink>; Hematology Department, Hospital de la Santa Creu i Sant Pau and Jose Carreras Leukemia Research Institute, Autonomus University of Barcelona, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Pallaud+C%22">Pallaud C</searchLink>; Novartis Pharmaceuticals, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Sanz+MA%22">Sanz MA</searchLink>; Hospital Universitario la Fe, Hematology Department, Department of Medicine, University of Valencia, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Jansen+JH%22">Jansen JH</searchLink>; Radboud Institute Molecular Studies, Radboud University Medical Center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Niederwieser+D%22">Niederwieser D</searchLink>; Hematology and Oncology, University of Leipzig, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Fischer+T%22">Fischer T</searchLink>; Department of Hematology and Oncology, Center of Internal Medicine, Otto-von-Guericke University Magdeburg, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ehninger+G%22">Ehninger G</searchLink>; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Heuser+M%22">Heuser M</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Ganser+A%22">Ganser A</searchLink>; Department of Hematology, Hemostasis, Oncology and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Bullinger+L%22">Bullinger L</searchLink>; Department of Hematology, Oncology and Tumor Immunology, Charité University, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Larson+RA%22">Larson RA</searchLink>; Department of Medicine and Comprehensive Cancer Center, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bloomfield+CD%22">Bloomfield CD</searchLink>; The Ohio State University Comprehensive Cancer Center, Columbus, OH, USA.<br /><searchLink fieldCode="AU" term="%22Stone+RM%22">Stone RM</searchLink>; Department of Medical Oncology, Dana-Farber/Partners CancerCare, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Döhner+H%22">Döhner H</searchLink>; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany.<br /><searchLink fieldCode="AU" term="%22Thiede+C%22">Thiede C</searchLink>; Medizinische Klinik und Poliklinik I, Universitätsklinikum Carl Gustav Carus der TU Dresden, Dresden, Germany.<br /><searchLink fieldCode="AU" term="%22Döhner+K%22">Döhner K</searchLink>; Department of Internal Medicine III, University Hospital of Ulm, Ulm, Germany. konstanze.doehner@uniklinik-ulm.de.
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  Data: <searchLink fieldCode="JN" term="%228704895%22">Leukemia</searchLink> [Leukemia] 2022 Jan; Vol. 36 (1), pp. 90-99. <i>Date of Electronic Publication: </i>2021 Jul 28.
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