Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profiling.
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| Title: | Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profiling. |
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| Authors: | Lyu Y; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA., Zauhar R; Department of Chemistry and Biochemistry, The University of the Sciences in Philadelphia, Philadelphia, PA, 19104, USA., Dana N; Departments of Ophthalmology and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA., Strang CE; Department of Psychology, University of Alabama At Birmingham, Birmingham, AL, 35294, USA., Hu J; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA., Wang K; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Information Theory and Data Science, School of Mathematical Sciences and LPMC, Nankai University, Tianjin, 30071, China., Liu S; Department of Biochemistry and Molecular Genetics, University of Alabama At Birmingham, Birmingham, AL, 35294, USA., Pan N; Department of Computer and Information Science, University of Pennsylvania, Philadelphia, PA, 19104, USA., Gamlin P; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA., Kimble JA; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA., Messinger JD; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA., Curcio CA; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA., Stambolian D; Departments of Ophthalmology and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. stamboli@pennmedicine.upenn.edu., Li M; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. mingyao@pennmedicine.upenn.edu. |
| Source: | Scientific reports [Sci Rep] 2021 Aug 02; Vol. 11 (1), pp. 15612. Date of Electronic Publication: 2021 Aug 02. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34341398 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profiling. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lyu+Y%22">Lyu Y</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Zauhar+R%22">Zauhar R</searchLink>; Department of Chemistry and Biochemistry, The University of the Sciences in Philadelphia, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Dana+N%22">Dana N</searchLink>; Departments of Ophthalmology and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Strang+CE%22">Strang CE</searchLink>; Department of Psychology, University of Alabama At Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Hu+J%22">Hu J</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Wang+K%22">Wang K</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA.; Department of Information Theory and Data Science, School of Mathematical Sciences and LPMC, Nankai University, Tianjin, 30071, China.<br /><searchLink fieldCode="AU" term="%22Liu+S%22">Liu S</searchLink>; Department of Biochemistry and Molecular Genetics, University of Alabama At Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Pan+N%22">Pan N</searchLink>; Department of Computer and Information Science, University of Pennsylvania, Philadelphia, PA, 19104, USA.<br /><searchLink fieldCode="AU" term="%22Gamlin+P%22">Gamlin P</searchLink>; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Kimble+JA%22">Kimble JA</searchLink>; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Messinger+JD%22">Messinger JD</searchLink>; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Curcio+CA%22">Curcio CA</searchLink>; Department of Ophthalmology and Visual Sciences, University of Alabama At Birmingham, Birmingham, AL, 35294, USA.<br /><searchLink fieldCode="AU" term="%22Stambolian+D%22">Stambolian D</searchLink>; Departments of Ophthalmology and Human Genetics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. stamboli@pennmedicine.upenn.edu.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Department of Biostatistics, Epidemiology and Informatics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, 19104, USA. mingyao@pennmedicine.upenn.edu. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101563288%22">Scientific reports</searchLink> [Sci Rep] 2021 Aug 02; Vol. 11 (1), pp. 15612. <i>Date of Electronic Publication: </i>2021 Aug 02. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101563288 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2045-2322 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220452322%22">20452322 </searchLink><i>NLM ISO Abbreviation: </i>Sci Rep |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34341398 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41598-021-95122-3 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 15612 Titles: – TitleFull: Implication of specific retinal cell-type involvement and gene expression changes in AMD progression using integrative analysis of single-cell and bulk RNA-seq profiling. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lyu Y – PersonEntity: Name: NameFull: Zauhar R – PersonEntity: Name: NameFull: Dana N – PersonEntity: Name: NameFull: Strang CE – PersonEntity: Name: NameFull: Hu J – PersonEntity: Name: NameFull: Wang K – PersonEntity: Name: NameFull: Liu S – PersonEntity: Name: NameFull: Pan N – PersonEntity: Name: NameFull: Gamlin P – PersonEntity: Name: NameFull: Kimble JA – PersonEntity: Name: NameFull: Messinger JD – PersonEntity: Name: NameFull: Curcio CA – PersonEntity: Name: NameFull: Stambolian D – PersonEntity: Name: NameFull: Li M IsPartOfRelationships: – BibEntity: Dates: – D: 02 M: 08 Text: 2021 Aug 02 Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 2045-2322 Numbering: – Type: volume Value: 11 – Type: issue Value: 1 Titles: – TitleFull: Scientific reports Type: main |
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