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Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial.

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Title: Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial.
Authors: Blauvelt A; Oregon Medical Research Center, Portland., Teixeira HD; AbbVie Inc, North Chicago, Illinois., Simpson EL; Department of Dermatology, Oregon Health & Science University, Portland., Costanzo A; Dermatology Unit, Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.; Humanitas Clinical and Research Center, Scientific Institute for Research, Hospitalization and Healthcare, Rozzano, Italy., De Bruin-Weller M; Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, the Netherlands., Barbarot S; Department of Dermatology, Nantes Université, Centre Hospitalier Universitaire de Nantes, Nantes, France., Prajapati VH; Division of Dermatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.; Division of Community Pediatrics, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Division of Pediatric Rheumatology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Skin Health & Wellness Centre, Calgary, Alberta, Canada.; Dermatology Research Institute, Calgary, Alberta, Canada.; Probity Medical Research, Calgary, Alberta, Canada., Lio P; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Medical Dermatology Associates of Chicago, Chicago, Illinois., Hu X; AbbVie Inc, North Chicago, Illinois., Wu T; AbbVie Inc, North Chicago, Illinois., Liu J; AbbVie Inc, North Chicago, Illinois., Ladizinski B; AbbVie Inc, North Chicago, Illinois., Chu AD; AbbVie Inc, North Chicago, Illinois., Eyerich K; Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
Source: JAMA dermatology [JAMA Dermatol] 2021 Sep 01; Vol. 157 (9), pp. 1047-1055.
Publication Type: Clinical Trial, Phase III; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Medical Association Country of Publication: United States NLM ID: 101589530 Publication Model: Print Cited Medium: Internet ISSN: 2168-6084 (Electronic) Linking ISSN: 21686068 NLM ISO Abbreviation: JAMA Dermatol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Efficacy and Safety of Upadacitinib vs Dupilumab in Adults With Moderate-to-Severe Atopic Dermatitis: A Randomized Clinical Trial.
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  Data: <searchLink fieldCode="AU" term="%22Blauvelt+A%22">Blauvelt A</searchLink>; Oregon Medical Research Center, Portland.<br /><searchLink fieldCode="AU" term="%22Teixeira+HD%22">Teixeira HD</searchLink>; AbbVie Inc, North Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Simpson+EL%22">Simpson EL</searchLink>; Department of Dermatology, Oregon Health & Science University, Portland.<br /><searchLink fieldCode="AU" term="%22Costanzo+A%22">Costanzo A</searchLink>; Dermatology Unit, Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Italy.; Humanitas Clinical and Research Center, Scientific Institute for Research, Hospitalization and Healthcare, Rozzano, Italy.<br /><searchLink fieldCode="AU" term="%22De+Bruin-Weller+M%22">De Bruin-Weller M</searchLink>; Department of Dermatology and Allergology, University Medical Center Utrecht, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Barbarot+S%22">Barbarot S</searchLink>; Department of Dermatology, Nantes Université, Centre Hospitalier Universitaire de Nantes, Nantes, France.<br /><searchLink fieldCode="AU" term="%22Prajapati+VH%22">Prajapati VH</searchLink>; Division of Dermatology, Department of Medicine, University of Calgary, Calgary, Alberta, Canada.; Division of Community Pediatrics, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Division of Pediatric Rheumatology, Department of Pediatrics, University of Calgary, Calgary, Alberta, Canada.; Skin Health & Wellness Centre, Calgary, Alberta, Canada.; Dermatology Research Institute, Calgary, Alberta, Canada.; Probity Medical Research, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Lio+P%22">Lio P</searchLink>; Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.; Medical Dermatology Associates of Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Hu+X%22">Hu X</searchLink>; AbbVie Inc, North Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Wu+T%22">Wu T</searchLink>; AbbVie Inc, North Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; AbbVie Inc, North Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Ladizinski+B%22">Ladizinski B</searchLink>; AbbVie Inc, North Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Chu+AD%22">Chu AD</searchLink>; AbbVie Inc, North Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Eyerich+K%22">Eyerich K</searchLink>; Karolinska Institutet and Karolinska University Hospital, Stockholm, Sweden.; Department of Dermatology and Allergy, Technical University of Munich, Munich, Germany.
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  Data: <searchLink fieldCode="JN" term="%22101589530%22">JAMA dermatology</searchLink> [JAMA Dermatol] 2021 Sep 01; Vol. 157 (9), pp. 1047-1055.
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