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Safety, Tolerability, and Pharmacokinetics of High-Volume Subcutaneous Crenezumab, With and Without Recombinant Human Hyaluronidase in Healthy Volunteers.

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Title: Safety, Tolerability, and Pharmacokinetics of High-Volume Subcutaneous Crenezumab, With and Without Recombinant Human Hyaluronidase in Healthy Volunteers.
Authors: Dolton MJ; Roche Products Pty Limited, Sydney, New South Wales, Australia., Chesterman A; Genentech, Inc., South San Francisco, California, USA., Moein A; Genentech, Inc., South San Francisco, California, USA., Sink KM; Genentech, Inc., South San Francisco, California, USA., Waitz A; Genentech, Inc., South San Francisco, California, USA., Blondeau K; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Kerchner GA; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Hu N; Genentech, Inc., South San Francisco, California, USA., Brooks L; Genentech, Inc., South San Francisco, California, USA., Wetzel-Smith MK; Genentech, Inc., South San Francisco, California, USA., Roden A; Genentech, Inc., South San Francisco, California, USA., Deshmukh A; Genentech, Inc., South San Francisco, California, USA., Peng K; Genentech, Inc., South San Francisco, California, USA., Carrasco-Triguero M; Genentech, Inc., South San Francisco, California, USA., Smith J; Roche Products Limited, Welwyn Garden City, UK., Ostrowitzki S; F. Hoffmann-La Roche Ltd, Basel, Switzerland., Quartino A; Genentech, Inc., South San Francisco, California, USA.
Source: Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2021 Nov; Vol. 110 (5), pp. 1337-1348. Date of Electronic Publication: 2021 Aug 27.
Publication Type: Clinical Trial, Phase I; Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE
Database: MEDLINE Ultimate
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