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Gemfibrozil derivatives as activators of soluble guanylyl cyclase - A structure-activity study.

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Title: Gemfibrozil derivatives as activators of soluble guanylyl cyclase - A structure-activity study.
Authors: Gayler KM; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Quintana JM; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Mattke J; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Plunk MA; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Kostyo JH; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Karunananthan JW; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Nguyen H; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Shuda M; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Ferreira LD; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Baker H; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Stinchcomb AL; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA., Sharina I; Department of Internal Medicine, Division of Cardiology, the University of Texas Health Science Center in Houston, McGoven Medical School, 1941 East Road, Houston, TX, 77054, USA., Kane RR; Department of Chemistry and Biochemistry, Institute of Biomedical Studies, Baylor University, Baylor University, Waco, TX, 76798, USA. Electronic address: Bob_kane@Baylor.edu., Martin E; Department of Internal Medicine, Division of Cardiology, the University of Texas Health Science Center in Houston, McGoven Medical School, 1941 East Road, Houston, TX, 77054, USA. Electronic address: emil.martin@uth.tmc.edu.
Source: European journal of medicinal chemistry [Eur J Med Chem] 2021 Nov 15; Vol. 224, pp. 113729. Date of Electronic Publication: 2021 Aug 03.
Publication Type: Journal Article
Journal Info: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE
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