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Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.

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Title: Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.
Authors: Ali R; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Alabdullah M; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK., Algethami M; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Alblihy A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Medical Center, King Fahad Security College (KFSC), Riyadh 11461, Saudi Arabia., Miligy I; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK., Shoqafi A; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Mesquita KA; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK., Abdel-Fatah T; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK., Chan SY; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK., Chiang PW; Department of Obstetrics & Gynaecology, Queens Medical Centre, Nottingham University Hospitals, Nottingham NG7 2UH, UK., Mongan NP; Faculty of Medicine and Health Sciences, Centre for Cancer Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire LE12 5RD, UK.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10065, USA., Rakha EA; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK., Tomkinson AE; Department of Internal Medicine, Division of Molecular Medicine, Health Sciences Center, The University of New Mexico, Albuquerque, NM 87102, USA., Madhusudan S; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK.
Source: Theranostics [Theranostics] 2021 Jul 25; Vol. 11 (17), pp. 8350-8361. Date of Electronic Publication: 2021 Jul 25 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ligase 1 is a predictor of platinum resistance and its blockade is synthetically lethal in XRCC1 deficient epithelial ovarian cancers.
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  Data: <searchLink fieldCode="AU" term="%22Ali+R%22">Ali R</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.<br /><searchLink fieldCode="AU" term="%22Alabdullah+M%22">Alabdullah M</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK.<br /><searchLink fieldCode="AU" term="%22Algethami+M%22">Algethami M</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.<br /><searchLink fieldCode="AU" term="%22Alblihy+A%22">Alblihy A</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Medical Center, King Fahad Security College (KFSC), Riyadh 11461, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Miligy+I%22">Miligy I</searchLink>; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK.<br /><searchLink fieldCode="AU" term="%22Shoqafi+A%22">Shoqafi A</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.<br /><searchLink fieldCode="AU" term="%22Mesquita+KA%22">Mesquita KA</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.<br /><searchLink fieldCode="AU" term="%22Abdel-Fatah+T%22">Abdel-Fatah T</searchLink>; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK.<br /><searchLink fieldCode="AU" term="%22Chan+SY%22">Chan SY</searchLink>; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK.<br /><searchLink fieldCode="AU" term="%22Chiang+PW%22">Chiang PW</searchLink>; Department of Obstetrics & Gynaecology, Queens Medical Centre, Nottingham University Hospitals, Nottingham NG7 2UH, UK.<br /><searchLink fieldCode="AU" term="%22Mongan+NP%22">Mongan NP</searchLink>; Faculty of Medicine and Health Sciences, Centre for Cancer Sciences, University of Nottingham, Sutton Bonington Campus, Sutton Bonington, Leicestershire LE12 5RD, UK.; Department of Pharmacology, Weill Cornell Medicine, New York, NY, 10065, USA.<br /><searchLink fieldCode="AU" term="%22Rakha+EA%22">Rakha EA</searchLink>; Department of Pathology, Division of Cancer and Stem Cells, School of Medicine, University of Nottingham, Nottingham NG51PB, UK.<br /><searchLink fieldCode="AU" term="%22Tomkinson+AE%22">Tomkinson AE</searchLink>; Department of Internal Medicine, Division of Molecular Medicine, Health Sciences Center, The University of New Mexico, Albuquerque, NM 87102, USA.<br /><searchLink fieldCode="AU" term="%22Madhusudan+S%22">Madhusudan S</searchLink>; Nottingham Biodiscovery Institute, School of Medicine, University of Nottingham, University Park, Nottingham NG7 3RD, UK.; Department of Oncology, Nottingham University Hospitals, City Hospital Campus, Nottingham NG5 1PB, UK.
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  Data: <searchLink fieldCode="JN" term="%22101552395%22">Theranostics</searchLink> [Theranostics] 2021 Jul 25; Vol. 11 (17), pp. 8350-8361. <i>Date of Electronic Publication: </i>2021 Jul 25 (<i>Print Publication: </i>2021).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Ivyspring+International+Publisher%22">Ivyspring International Publisher </searchLink><i>Country of Publication: </i>Australia <i>NLM ID: </i>101552395 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1838-7640 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2218387640%22">18387640 </searchLink><i>NLM ISO Abbreviation: </i>Theranostics <i>Subsets: </i>MEDLINE
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