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Rationale, design, demographics and baseline characteristics of the randomized, controlled, Phase 2b SAPPHIRE study of verinurad plus allopurinol in patients with chronic kidney disease and hyperuricaemia.

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Title: Rationale, design, demographics and baseline characteristics of the randomized, controlled, Phase 2b SAPPHIRE study of verinurad plus allopurinol in patients with chronic kidney disease and hyperuricaemia.
Authors: Heerspink HJL; Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; The George Institute for Global Health, Sydney, Australia., Stack AG; School of Medicine & Health Research Institute, University of Limerick, Limerick, Ireland., Terkeltaub R; San Francisco VA Health Care System, University of California San Diego, La Jolla, CA, USA., Greene TA; University of Utah School of Medicine, Salt Lake City, UT, USA., Inker LA; Tufts Medical Center, Boston, MA, USA., Bjursell M; AstraZeneca R&D Gothenburg, Mölndal, Sweden., Perl S; AstraZeneca R&D, Gaithersburg, MD, USA., Rikte T; AstraZeneca R&D Gothenburg, Mölndal, Sweden., Erlandsson F; AstraZeneca R&D Gothenburg, Mölndal, Sweden., Perkovic V; The George Institute for Global Health, Sydney, Australia.
Source: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association [Nephrol Dial Transplant] 2022 Jul 26; Vol. 37 (8), pp. 1461-1471.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8706402 Publication Model: Print Cited Medium: Internet ISSN: 1460-2385 (Electronic) Linking ISSN: 09310509 NLM ISO Abbreviation: Nephrol Dial Transplant Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1460-2385
DOI:10.1093/ndt/gfab237