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AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms.

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Title: AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms.
Authors: Beitzen-Heineke A; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Berenbrok N; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Waizenegger J; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Paesler S; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Gensch V; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Udonta F; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Vargas Delgado ME; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany., Engelmann J; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Hoffmann F; Practice for Hematology and Oncology Altona, Hamburg, Germany., Schafhausen P; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany., von Amsberg G; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany., Riecken K; Department of Stem Cell Transplantation, Research Department Cell and Gene Therapy, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Beumer N; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Applied Bioinformatics, German Cancer Research Center (Deutsches Krebsforschungszentrum; DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany., Imbusch CD; Division of Applied Bioinformatics, German Cancer Research Center (Deutsches Krebsforschungszentrum; DKFZ), Heidelberg, Germany., Lorens J; Department of Biomedicine, Centre for Cancer Biomarkers, Norwegian Centre of Excellence, University of Bergen, Norway.; BerGenBio ASA, Bergen, Norway., Fischer T; Department of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg, Germany., Pantel K; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Bokemeyer C; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany., Ben-Batalla I; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany., Loges S; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
Source: HemaSphere [Hemasphere] 2021 Aug 11; Vol. 5 (9), pp. e630. Date of Electronic Publication: 2021 Aug 11 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: AXL Inhibition Represents a Novel Therapeutic Approach in BCR-ABL Negative Myeloproliferative Neoplasms.
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  Data: <searchLink fieldCode="AU" term="%22Beitzen-Heineke+A%22">Beitzen-Heineke A</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Berenbrok+N%22">Berenbrok N</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Waizenegger+J%22">Waizenegger J</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Paesler+S%22">Paesler S</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gensch+V%22">Gensch V</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Udonta+F%22">Udonta F</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Vargas+Delgado+ME%22">Vargas Delgado ME</searchLink>; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Engelmann+J%22">Engelmann J</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Hoffmann+F%22">Hoffmann F</searchLink>; Practice for Hematology and Oncology Altona, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Schafhausen+P%22">Schafhausen P</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22von+Amsberg+G%22">von Amsberg G</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Riecken+K%22">Riecken K</searchLink>; Department of Stem Cell Transplantation, Research Department Cell and Gene Therapy, University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Beumer+N%22">Beumer N</searchLink>; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Division of Applied Bioinformatics, German Cancer Research Center (Deutsches Krebsforschungszentrum; DKFZ), Heidelberg, Germany.; Faculty of Biosciences, Heidelberg University, Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Imbusch+CD%22">Imbusch CD</searchLink>; Division of Applied Bioinformatics, German Cancer Research Center (Deutsches Krebsforschungszentrum; DKFZ), Heidelberg, Germany.<br /><searchLink fieldCode="AU" term="%22Lorens+J%22">Lorens J</searchLink>; Department of Biomedicine, Centre for Cancer Biomarkers, Norwegian Centre of Excellence, University of Bergen, Norway.; BerGenBio ASA, Bergen, Norway.<br /><searchLink fieldCode="AU" term="%22Fischer+T%22">Fischer T</searchLink>; Department of Hematology and Oncology, Medical Center, Otto-von-Guericke University, Magdeburg, Germany.<br /><searchLink fieldCode="AU" term="%22Pantel+K%22">Pantel K</searchLink>; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bokemeyer+C%22">Bokemeyer C</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Ben-Batalla+I%22">Ben-Batalla I</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.<br /><searchLink fieldCode="AU" term="%22Loges+S%22">Loges S</searchLink>; Department for Oncology, Hematology and Bone Marrow Transplantation with the Section Pneumology, Hubertus Wald Tumorzentrum, University Comprehensive Cancer Center Hamburg, Germany.; Department of Tumor Biology, Center of Experimental Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.; Division of Personalized Medical Oncology, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Department of Personalized Oncology, University Hospital Mannheim, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany.
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