Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.

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Title: Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.
Authors: Aiderus A; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America., Newberg JY; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America., Guzman-Rojas L; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America., Contreras-Sandoval AM; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America., Meshey AL; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America., Jones DJ; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America., Amaya-Manzanares F; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America., Rangel R; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America., Ward JM; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Lee SC; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Ban KH; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Rogers K; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Rogers SM; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Selvanesan L; Centre for Translational Cancer Research, Department of Biochemistry, University of Otago, Dunedin, New Zealand., McNoe LA; Centre for Translational Cancer Research, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Copeland NG; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Jenkins NA; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore., Tsai KY; Departments of Anatomic Pathology & Tumor Biology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Donald A. Adam Melanoma and Skin Cancer Research Center of Excellence, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America., Black MA; Centre for Translational Cancer Research, Department of Biochemistry, University of Otago, Dunedin, New Zealand., Mann KM; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.; Departments of Gastrointestinal Oncology & Malignant Hematology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Biology and Evolution Program, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America., Mann MB; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.; Donald A. Adam Melanoma and Skin Cancer Research Center of Excellence, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.; Cancer Biology and Evolution Program, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Cutaneous Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.
Source: PLoS genetics [PLoS Genet] 2021 Aug 16; Vol. 17 (8), pp. e1009094. Date of Electronic Publication: 2021 Aug 16 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101239074 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7404 (Electronic) Linking ISSN: 15537390 NLM ISO Abbreviation: PLoS Genet Subsets: MEDLINE
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  Data: Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression.
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  Data: <searchLink fieldCode="AU" term="%22Aiderus+A%22">Aiderus A</searchLink>; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Newberg+JY%22">Newberg JY</searchLink>; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Guzman-Rojas+L%22">Guzman-Rojas L</searchLink>; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Contreras-Sandoval+AM%22">Contreras-Sandoval AM</searchLink>; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Meshey+AL%22">Meshey AL</searchLink>; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Jones+DJ%22">Jones DJ</searchLink>; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Amaya-Manzanares+F%22">Amaya-Manzanares F</searchLink>; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Rangel+R%22">Rangel R</searchLink>; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.<br /><searchLink fieldCode="AU" term="%22Ward+JM%22">Ward JM</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Lee+SC%22">Lee SC</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Ban+KH%22">Ban KH</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Rogers+K%22">Rogers K</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Rogers+SM%22">Rogers SM</searchLink>; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Selvanesan+L%22">Selvanesan L</searchLink>; Centre for Translational Cancer Research, Department of Biochemistry, University of Otago, Dunedin, New Zealand.<br /><searchLink fieldCode="AU" term="%22McNoe+LA%22">McNoe LA</searchLink>; Centre for Translational Cancer Research, Department of Biochemistry, University of Otago, Dunedin, New Zealand.<br /><searchLink fieldCode="AU" term="%22Copeland+NG%22">Copeland NG</searchLink>; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Jenkins+NA%22">Jenkins NA</searchLink>; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.<br /><searchLink fieldCode="AU" term="%22Tsai+KY%22">Tsai KY</searchLink>; Departments of Anatomic Pathology & Tumor Biology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Donald A. Adam Melanoma and Skin Cancer Research Center of Excellence, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Black+MA%22">Black MA</searchLink>; Centre for Translational Cancer Research, Department of Biochemistry, University of Otago, Dunedin, New Zealand.<br /><searchLink fieldCode="AU" term="%22Mann+KM%22">Mann KM</searchLink>; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.; Departments of Gastrointestinal Oncology & Malignant Hematology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Biology and Evolution Program, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.<br /><searchLink fieldCode="AU" term="%22Mann+MB%22">Mann MB</searchLink>; Department of Molecular Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Cancer Research Program, Houston Methodist Research Institute, Houston, Texas, United States of America.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore, Republic of Singapore.; Donald A. Adam Melanoma and Skin Cancer Research Center of Excellence, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Oncologic Sciences, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America.; Cancer Biology and Evolution Program, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.; Department of Cutaneous Oncology, Moffitt Cancer Center & Research Institute, Tampa, Florida, United States of America.
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  Data: <searchLink fieldCode="JN" term="%22101239074%22">PLoS genetics</searchLink> [PLoS Genet] 2021 Aug 16; Vol. 17 (8), pp. e1009094. <i>Date of Electronic Publication: </i>2021 Aug 16 (<i>Print Publication: </i>2021).
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