Granzyme A Produced by γ9δ2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity.

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Title: Granzyme A Produced by γ9δ2 T Cells Activates ER Stress Responses and ATP Production, and Protects Against Intracellular Mycobacterial Replication Independent of Enzymatic Activity.
Authors: Rasi V; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, United States.; Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States., Wood DC; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, United States., Eickhoff CS; Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States., Xia M; Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States., Pozzi N; Department of Biochemistry and Molecular Biology, Saint Louis University School of Medicine, Saint Louis, MO, United States., Edwards RL; Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States., Walch M; Anatomy Unit, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland., Bovenschen N; Department of Pathology, University Medical Center Utrecht, Utrecht, Netherlands.; Center for Translational Immunology, University Medical Center Utrecht, Utrecht, Netherlands., Hoft DF; Department of Molecular Microbiology and Immunology, Saint Louis University School of Medicine, Saint Louis, MO, United States.; Department of Internal Medicine, Saint Louis University School of Medicine, Saint Louis, MO, United States.
Source: Frontiers in immunology [Front Immunol] 2021 Aug 03; Vol. 12, pp. 712678. Date of Electronic Publication: 2021 Aug 03 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2021.712678