Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer.

Saved in:
Bibliographic Details
Title: Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer.
Authors: Lafferty A; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland., O'Farrell AC; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland., Migliardi G; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Khemka N; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Lindner AU; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Sassi F; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Zanella ER; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Salvucci M; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Vanderheyden E; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium., Modave E; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium., Boeckx B; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium., Halang L; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Betge J; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.; Junior Clinical Cooperation Unit Translational Gastrointestinal Oncology and Preclinical Models, German Cancer Research Center (DKFZ), Heidelberg, Germany., Ebert MPA; Department of Medicine II, Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany., Dicker P; Department of Epidemiology and Public Health Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Argilés G; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain., Tabernero J; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain., Dienstmann R; Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, CIBERONC, Barcelona, Spain., Medico E; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Lambrechts D; Department of Human Genetics, VIB Center for Cancer Biology, Leuven, Belgium, Laboratory for Translational Genetics, KU Leuven, Leuven, Belgium., Bertotti A; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Isella C; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Trusolino L; Department of Oncology, University of Torino, Candiolo, Italy.; Candiolo Cancer Institute, FPO-IRCCS, Candiolo, Italy., Prehn JHM; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; Center for Systems Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland., Byrne AT; Department of Physiology and Medical Physics, Precision Cancer Medicine Group, Royal College of Surgeons in Ireland, Dublin, Ireland. annettebyrne@rcsi.ie.; Department of Physiology and Medical Physics, Royal College of Surgeons in Ireland, Dublin, Ireland.; UCD School of Biomolecular and Biomedical Science, UCD Conway Institute, University College Dublin, Belfield, Dublin, Ireland.
Source: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Nov 01; Vol. 27 (21), pp. 5979-5992. Date of Electronic Publication: 2021 Aug 23.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1557-3265
DOI:10.1158/1078-0432.CCR-21-0818