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Spatially organized multicellular immune hubs in human colorectal cancer.

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Title: Spatially organized multicellular immune hubs in human colorectal cancer.
Authors: Pelka K; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA., Hofree M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Chen JH; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA; Department of Pathology, MGH, Boston, MA, USA., Sarkizova S; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Pirl JD; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Jorgji V; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA; Department of Pathology, MGH, Boston, MA, USA., Bejnood A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dionne D; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ge WH; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Xu KH; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA., Chao SX; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Department of Biomedical Informatics, HMS, Boston, MA, USA., Zollinger DR; NanoString Technologies Inc., Seattle, WA, USA., Lieb DJ; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Reeves JW; NanoString Technologies Inc., Seattle, WA, USA., Fuhrman CA; NanoString Technologies Inc., Seattle, WA, USA., Hoang ML; NanoString Technologies Inc., Seattle, WA, USA., Delorey T; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen LT; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Waldman J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Klapholz M; Evergrande Center for Immunologic Diseases, HMS and Brigham and Women's Hospital (BWH), Boston, MA, USA., Wakiro I; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Cohen O; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA; Department of Medical Oncology, DFCI, Boston, MA, USA., Albers J; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Smillie CS; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Cuoco MS; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Wu J; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Su MJ; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Yeung J; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Vijaykumar B; Department of Immunology, HMS, Boston, MA, USA., Magnuson AM; Department of Immunology, HMS, Boston, MA, USA., Asinovski N; Department of Immunology, HMS, Boston, MA, USA., Moll T; Clinical Research Center, MGH, Boston, MA, USA., Goder-Reiser MN; Clinical Research Center, MGH, Boston, MA, USA., Applebaum AS; Clinical Research Center, MGH, Boston, MA, USA., Brais LK; Clinical Research Center, DFCI, Boston, MA, USA., DelloStritto LK; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Denning SL; Clinical Research Center, DFCI, Boston, MA, USA., Phillips ST; Clinical Research Center, MGH, Boston, MA, USA., Hill EK; Clinical Research Center, DFCI, Boston, MA, USA., Meehan JK; Clinical Research Center, DFCI, Boston, MA, USA., Frederick DT; Clinical Research Center, MGH, Boston, MA, USA., Sharova T; Clinical Research Center, MGH, Boston, MA, USA., Kanodia A; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Todres EZ; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA., Jané-Valbuena J; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Biton M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Department of Molecular Biology, MGH, Boston, MA, USA., Izar B; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA; Department of Medical Oncology, DFCI, Boston, MA, USA., Lambden CD; Evergrande Center for Immunologic Diseases, HMS and Brigham and Women's Hospital (BWH), Boston, MA, USA., Clancy TE; Department of Surgery, BWH, Boston, MA, USA., Bleday R; Department of Surgery, BWH, Boston, MA, USA., Melnitchouk N; Department of Surgery, BWH, Boston, MA, USA., Irani J; Department of Surgery, BWH, Boston, MA, USA., Kunitake H; Department of Surgery, MGH, Boston, MA, USA., Berger DL; Department of Surgery, MGH, Boston, MA, USA., Srivastava A; Department of Pathology, BWH, Boston, MA, USA., Hornick JL; Department of Pathology, BWH, Boston, MA, USA., Ogino S; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Department of Pathology, BWH, Boston, MA, USA., Rotem A; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Vigneau S; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA., Johnson BE; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA; Department of Medical Oncology, DFCI, Boston, MA, USA., Corcoran RB; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA; Department of Medicine, HMS, Boston, MA, USA., Sharpe AH; Evergrande Center for Immunologic Diseases, HMS and Brigham and Women's Hospital (BWH), Boston, MA, USA; Department of Immunology, Blavatnik Institute, HMS, Boston, MA, USA., Kuchroo VK; Evergrande Center for Immunologic Diseases, HMS and Brigham and Women's Hospital (BWH), Boston, MA, USA., Ng K; Department of Medical Oncology, DFCI, Boston, MA, USA., Giannakis M; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Department of Medical Oncology, DFCI, Boston, MA, USA., Nieman LT; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA., Boland GM; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA; Department of Surgery, MGH, Boston, MA, USA., Aguirre AJ; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Department of Medical Oncology, DFCI, Boston, MA, USA., Anderson AC; Evergrande Center for Immunologic Diseases, HMS and Brigham and Women's Hospital (BWH), Boston, MA, USA. Electronic address: acanderson@bwh.harvard.edu., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: orit@broadinstitute.org., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA; Howard Hughes Medical Institute and Koch Institute for Integrative Cancer Research, Department of Biology, MIT, Cambridge, MA, USA. Electronic address: aviv.regev.sc@gmail.com., Hacohen N; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA; Department of Immunology, HMS, Boston, MA, USA. Electronic address: nhacohen@mgh.harvard.edu.
Source: Cell [Cell] 2021 Sep 02; Vol. 184 (18), pp. 4734-4752.e20. Date of Electronic Publication: 2021 Aug 26.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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DbLabel: MEDLINE Ultimate
An: 34450029
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Spatially organized multicellular immune hubs in human colorectal cancer.
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Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Jorgji+V%22">Jorgji V</searchLink>; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA; Department of Pathology, MGH, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Bejnood+A%22">Bejnood A</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Dionne+D%22">Dionne D</searchLink>; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Ge+WH%22">Ge WH</searchLink>; Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard, Cambridge, MA, USA.<br /><searchLink fieldCode="AU" term="%22Xu+KH%22">Xu KH</searchLink>; Massachusetts General Hospital (MGH) Cancer Center, Harvard Medical School (HMS), Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chao+SX%22">Chao SX</searchLink>; 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Department of Immunology, HMS, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Magnuson+AM%22">Magnuson AM</searchLink>; Department of Immunology, HMS, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Asinovski+N%22">Asinovski N</searchLink>; Department of Immunology, HMS, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Moll+T%22">Moll T</searchLink>; Clinical Research Center, MGH, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Goder-Reiser+MN%22">Goder-Reiser MN</searchLink>; Clinical Research Center, MGH, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Applebaum+AS%22">Applebaum AS</searchLink>; Clinical Research Center, MGH, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Brais+LK%22">Brais LK</searchLink>; Clinical Research Center, DFCI, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22DelloStritto+LK%22">DelloStritto LK</searchLink>; Center for Cancer Genomics, Department of Medical Oncology, Dana-Farber Cancer Institute (DFCI), Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Denning+SL%22">Denning SL</searchLink>; 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  Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2021 Sep 02; Vol. 184 (18), pp. 4734-4752.e20. <i>Date of Electronic Publication: </i>2021 Aug 26.
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      – TitleFull: Spatially organized multicellular immune hubs in human colorectal cancer.
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    IsPartOfRelationships:
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          Dates:
            – D: 02
              M: 09
              Text: 2021 Sep 02
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1097-4172
          Numbering:
            – Type: volume
              Value: 184
            – Type: issue
              Value: 18
          Titles:
            – TitleFull: Cell
              Type: main
ResultId 1