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Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo.

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Title: Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo.
Authors: Liu Z; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26505, USA., Shah N; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.; School of Medicine, West Virginia University, Morgantown, USA., Marshall KL; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26505, USA.; School of Medicine, West Virginia University, Morgantown, USA.; West Virginia Clinical and Translational Science Institute, Morgantown, USA., Sprowls SA; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA., Saralkar P; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA., Mohammad A; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA., Blethen KE; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA., Arsiwala TA; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA., Fladeland R; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA., Lockman PR; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA. prlockman@hsc.wvu.edu., Gao W; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26505, USA. weimin.gao@hsc.wvu.edu.
Source: Archives of toxicology [Arch Toxicol] 2021 Nov; Vol. 95 (11), pp. 3575-3587. Date of Electronic Publication: 2021 Aug 28.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Overcoming the acquired resistance to gefitinib in lung cancer brain metastasis in vitro and in vivo.
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  Data: <searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26505, USA.<br /><searchLink fieldCode="AU" term="%22Shah+N%22">Shah N</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.; School of Medicine, West Virginia University, Morgantown, USA.<br /><searchLink fieldCode="AU" term="%22Marshall+KL%22">Marshall KL</searchLink>; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26505, USA.; School of Medicine, West Virginia University, Morgantown, USA.; West Virginia Clinical and Translational Science Institute, Morgantown, USA.<br /><searchLink fieldCode="AU" term="%22Sprowls+SA%22">Sprowls SA</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.<br /><searchLink fieldCode="AU" term="%22Saralkar+P%22">Saralkar P</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.<br /><searchLink fieldCode="AU" term="%22Mohammad+A%22">Mohammad A</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.<br /><searchLink fieldCode="AU" term="%22Blethen+KE%22">Blethen KE</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.<br /><searchLink fieldCode="AU" term="%22Arsiwala+TA%22">Arsiwala TA</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.<br /><searchLink fieldCode="AU" term="%22Fladeland+R%22">Fladeland R</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA.<br /><searchLink fieldCode="AU" term="%22Lockman+PR%22">Lockman PR</searchLink>; Department of Basic Pharmaceutical Sciences, School of Pharmacy, West Virginia University, 108 Biomedical Drive, Morgantown, WV, 26506, USA. prlockman@hsc.wvu.edu.<br /><searchLink fieldCode="AU" term="%22Gao+W%22">Gao W</searchLink>; Department of Occupational and Environmental Health Sciences, School of Public Health, West Virginia University, 64 Medical Center Drive, Morgantown, WV, 26505, USA. weimin.gao@hsc.wvu.edu.
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