Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption.
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| Title: | Physiologically Based Pharmacokinetic Modelling of Inhaled Nemiralisib: Mechanistic Components for Pulmonary Absorption, Systemic Distribution, and Oral Absorption. |
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| Authors: | Miller NA; Simulations Plus, Inc., 42505 10th Street West, Lancaster, CA, 93534, USA. neil@simulations-plus.com., Graves RH; Simulations Plus, Inc., 42505 10th Street West, Lancaster, CA, 93534, USA., Edwards CD; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., Amour A; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., Taylor E; GlaxoSmithKline R&D, Gunnelswood Road, Ware, Hertfordshire, UK., Robb O; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., O'Brien B; GlaxoSmithKline R&D, Stevenage, Hertfordshire, UK., Patel A; GlaxoSmithKline R&D, Gunnelswood Road, Ware, Hertfordshire, UK., Harrell AW; GlaxoSmithKline R&D, Gunnelswood Road, Ware, Hertfordshire, UK., Hessel EM; Eligo Bioscience, Paris, France. |
| Source: | Clinical pharmacokinetics [Clin Pharmacokinet] 2022 Feb; Vol. 61 (2), pp. 281-293. Date of Electronic Publication: 2021 Aug 30. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Adis, part of Springer Science+Business Media Country of Publication: Switzerland NLM ID: 7606849 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1926 (Electronic) Linking ISSN: 03125963 NLM ISO Abbreviation: Clin Pharmacokinet Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1179-1926 |
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| DOI: | 10.1007/s40262-021-01066-2 |
