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Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society.

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Title: Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society.
Authors: Ginsberg HN; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, PH-10-305, New York, NY 10032, USA., Packard CJ; Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK., Chapman MJ; Sorbonne University Endocrinology-Metabolism Division, Pitié-Salpetriere University Hospital, and National Institute for Health and Medical Research (INSERM), 47 Hôpital boulevard, Paris 75013, France., Borén J; Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Blå Stråket 5, Gothenburg 413 45, Sweden., Aguilar-Salinas CA; Unidad de Investigación en Enfermedades Metabólicas and Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubir án, Vasco de Quiroga 15, Belisario Domínguez Secc 16, Tlalpan, Mexico City 14080, Mexico.; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Ave. Morones Prieto, Monterrey, Nuevo León 3000, Mexico., Averna M; Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities, University of Palermo, Marina Square, 61, Palermo 90133, Italy., Ference BA; Centre for Naturally Randomized Trials, University of Cambridge, Cambridge, UK., Gaudet D; Clinical Lipidology and Rare Lipid Disorders Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal, ECOGENE, Clinical and Translational Research Center, and Lipid Clinic, Chicoutimi Hospital, 305 Rue St Vallier, Chicoutimi, Québec G7H 5H6, Canada., Hegele RA; Department of Medicine and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western Universi ty, 1151 Richmond Street, London, Ontario N6A 3K7, Canada., Kersten S; Division of Human Nutrition and Health, Wageningen University, Wageningen, the Netherlands., Lewis GF; Division of Endocrinology, Department of Medicine, Banting & Best Diabetes Centre, University of Toronto, Eaton Building, Room 12E248, 200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada., Lichtenstein AH; Cardiovascular Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St Ste 9, Boston, MA 02111, USA., Moulin P; Department of Endocrinology, GHE, Hospices Civils de Lyon, CarMeN Laboratory, Inserm UMR 1060, CENS-ELI B, Univ-Lyon1, Lyon 69003, France., Nordestgaard BG; Department of Clinical Biochemistry, Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, Herlev 2730, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen DK-2200, Denmark., Remaley AT; Lipoprotein Metabolism Section, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 31 Center Dr Ste 10-7C114, Bethesda, MD 20892, USA., Staels B; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France., Stroes ESG; Department of Vascular Medicine, Academic Medical Center, 1541 Kings Hwy, Amsterdam 71103, The Netherlands., Taskinen MR; Research Programs Unit, Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland., Tokgözoğlu LS; Department of Cardiology, Hacettepe University Faculty of Medicine, 06100 Sıhhiye, Ankara, Turkey., Tybjaerg-Hansen A; Department of Clinical Biochemistry, Blegdamsvej 9, Rigshospitalet, Copenhagen 2100, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Herlev, Denmark.; Copenhagen City Heart Study, Frederiksberg Hospital, Nordre Fasanvej, Frederiksberg 57 2000, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej, Copenhagen 3B 2200, Denmark., Stock JK; European Atherosclerosis Society, Mässans Gata 10, Gothenburg SE-412 51, Sweden., Catapano AL; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano and IRCCS MultiMedica, Via Festa del Perdono 7, Milan 20122, Italy.
Source: European heart journal [Eur Heart J] 2021 Dec 14; Vol. 42 (47), pp. 4791-4806.
Publication Type: Journal Article; Consensus Statement
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 8006263 Publication Model: Print Cited Medium: Internet ISSN: 1522-9645 (Electronic) Linking ISSN: 0195668X NLM ISO Abbreviation: Eur Heart J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Triglyceride-rich lipoproteins and their remnants: metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies-a consensus statement from the European Atherosclerosis Society.
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  Data: <searchLink fieldCode="AU" term="%22Ginsberg+HN%22">Ginsberg HN</searchLink>; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, 630 West 168th Street, PH-10-305, New York, NY 10032, USA.<br /><searchLink fieldCode="AU" term="%22Packard+CJ%22">Packard CJ</searchLink>; Institute of Cardiovascular and Medical Sciences, University of Glasgow, 126 University Place, Glasgow G12 8TA, UK.<br /><searchLink fieldCode="AU" term="%22Chapman+MJ%22">Chapman MJ</searchLink>; Sorbonne University Endocrinology-Metabolism Division, Pitié-Salpetriere University Hospital, and National Institute for Health and Medical Research (INSERM), 47 Hôpital boulevard, Paris 75013, France.<br /><searchLink fieldCode="AU" term="%22Borén+J%22">Borén J</searchLink>; Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Blå Stråket 5, Gothenburg 413 45, Sweden.<br /><searchLink fieldCode="AU" term="%22Aguilar-Salinas+CA%22">Aguilar-Salinas CA</searchLink>; Unidad de Investigación en Enfermedades Metabólicas and Departamento de Endocrinología y Metabolismo, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubir án, Vasco de Quiroga 15, Belisario Domínguez Secc 16, Tlalpan, Mexico City 14080, Mexico.; Tecnologico de Monterrey, Escuela de Medicina y Ciencias de la Salud, Ave. Morones Prieto, Monterrey, Nuevo León 3000, Mexico.<br /><searchLink fieldCode="AU" term="%22Averna+M%22">Averna M</searchLink>; Department of Health Promotion Sciences Maternal and Infantile Care, Internal Medicine and Medical Specialities, University of Palermo, Marina Square, 61, Palermo 90133, Italy.<br /><searchLink fieldCode="AU" term="%22Ference+BA%22">Ference BA</searchLink>; Centre for Naturally Randomized Trials, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Gaudet+D%22">Gaudet D</searchLink>; Clinical Lipidology and Rare Lipid Disorders Unit, Community Genomic Medicine Center, Department of Medicine, Université de Montréal, ECOGENE, Clinical and Translational Research Center, and Lipid Clinic, Chicoutimi Hospital, 305 Rue St Vallier, Chicoutimi, Québec G7H 5H6, Canada.<br /><searchLink fieldCode="AU" term="%22Hegele+RA%22">Hegele RA</searchLink>; Department of Medicine and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western Universi ty, 1151 Richmond Street, London, Ontario N6A 3K7, Canada.<br /><searchLink fieldCode="AU" term="%22Kersten+S%22">Kersten S</searchLink>; Division of Human Nutrition and Health, Wageningen University, Wageningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Lewis+GF%22">Lewis GF</searchLink>; Division of Endocrinology, Department of Medicine, Banting & Best Diabetes Centre, University of Toronto, Eaton Building, Room 12E248, 200 Elizabeth St, Toronto, Ontario M5G 2C4, Canada.<br /><searchLink fieldCode="AU" term="%22Lichtenstein+AH%22">Lichtenstein AH</searchLink>; Cardiovascular Nutrition, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, 711 Washington St Ste 9, Boston, MA 02111, USA.<br /><searchLink fieldCode="AU" term="%22Moulin+P%22">Moulin P</searchLink>; Department of Endocrinology, GHE, Hospices Civils de Lyon, CarMeN Laboratory, Inserm UMR 1060, CENS-ELI B, Univ-Lyon1, Lyon 69003, France.<br /><searchLink fieldCode="AU" term="%22Nordestgaard+BG%22">Nordestgaard BG</searchLink>; Department of Clinical Biochemistry, Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev Ringvej 75, Herlev 2730, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, Copenhagen DK-2200, Denmark.<br /><searchLink fieldCode="AU" term="%22Remaley+AT%22">Remaley AT</searchLink>; Lipoprotein Metabolism Section, Translational Vascular Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, 31 Center Dr Ste 10-7C114, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Staels+B%22">Staels B</searchLink>; Univ. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France.<br /><searchLink fieldCode="AU" term="%22Stroes+ESG%22">Stroes ESG</searchLink>; Department of Vascular Medicine, Academic Medical Center, 1541 Kings Hwy, Amsterdam 71103, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Taskinen+MR%22">Taskinen MR</searchLink>; Research Programs Unit, Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland.<br /><searchLink fieldCode="AU" term="%22Tokgözoğlu+LS%22">Tokgözoğlu LS</searchLink>; Department of Cardiology, Hacettepe University Faculty of Medicine, 06100 Sıhhiye, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Tybjaerg-Hansen+A%22">Tybjaerg-Hansen A</searchLink>; Department of Clinical Biochemistry, Blegdamsvej 9, Rigshospitalet, Copenhagen 2100, Denmark.; Copenhagen General Population Study, Herlev and Gentofte Hospital, Herlev, Denmark.; Copenhagen City Heart Study, Frederiksberg Hospital, Nordre Fasanvej, Frederiksberg 57 2000, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej, Copenhagen 3B 2200, Denmark.<br /><searchLink fieldCode="AU" term="%22Stock+JK%22">Stock JK</searchLink>; European Atherosclerosis Society, Mässans Gata 10, Gothenburg SE-412 51, Sweden.<br /><searchLink fieldCode="AU" term="%22Catapano+AL%22">Catapano AL</searchLink>; Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano and IRCCS MultiMedica, Via Festa del Perdono 7, Milan 20122, Italy.
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