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PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis.

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Title: PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis.
Authors: Sandborn WJ; University of California-San Diego, San Diego, California., Mattheakis LC; Protagonist Therapeutics, Inc, Newark, California., Modi NB; Protagonist Therapeutics, Inc, Newark, California., Pugatch D; Finch Therapeutics, Inc, Somerville, Massachusetts., Bressler B; University of British Columbia, Vancouver, Canada., Lee S; University of Washington, Seattle, Washington., Bhandari R; Delta Research Partners, Bastrop, Louisiana., Kanwar B; Applied Molecular Transport, San Francisco, California., Shames R; Siolta, San Carlos, California., D'Haens G; Faculty of Medicine, University of Amsterdam, Amsterdam, the Netherlands., Schreiber S; University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany., Danese S; Humanitas University, Humanitas Research Hospital, Milan, Italy., Feagan B; Western University, Pomona, California and Alimentiv, Inc, London, Ontario, Canada., Pai RK; Mayo Clinic Arizona, Phoenix, Arizona., Liu DY; Protagonist Therapeutics, Inc, Newark, California., Gupta S; Protagonist Therapeutics, Inc, Newark, California. Electronic address: s.gupta@ptgx-inc.com.
Source: Gastroenterology [Gastroenterology] 2021 Dec; Vol. 161 (6), pp. 1853-1864.e10. Date of Electronic Publication: 2021 Aug 30.
Publication Type: Clinical Trial, Phase I; Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
Journal Info: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PTG-100, an Oral α4β7 Antagonist Peptide: Preclinical Development and Phase 1 and 2a Studies in Ulcerative Colitis.
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  Data: <searchLink fieldCode="AU" term="%22Sandborn+WJ%22">Sandborn WJ</searchLink>; University of California-San Diego, San Diego, California.<br /><searchLink fieldCode="AU" term="%22Mattheakis+LC%22">Mattheakis LC</searchLink>; Protagonist Therapeutics, Inc, Newark, California.<br /><searchLink fieldCode="AU" term="%22Modi+NB%22">Modi NB</searchLink>; Protagonist Therapeutics, Inc, Newark, California.<br /><searchLink fieldCode="AU" term="%22Pugatch+D%22">Pugatch D</searchLink>; Finch Therapeutics, Inc, Somerville, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Bressler+B%22">Bressler B</searchLink>; University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; University of Washington, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Bhandari+R%22">Bhandari R</searchLink>; Delta Research Partners, Bastrop, Louisiana.<br /><searchLink fieldCode="AU" term="%22Kanwar+B%22">Kanwar B</searchLink>; Applied Molecular Transport, San Francisco, California.<br /><searchLink fieldCode="AU" term="%22Shames+R%22">Shames R</searchLink>; Siolta, San Carlos, California.<br /><searchLink fieldCode="AU" term="%22D'Haens+G%22">D'Haens G</searchLink>; Faculty of Medicine, University of Amsterdam, Amsterdam, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Schreiber+S%22">Schreiber S</searchLink>; University Hospital Schleswig-Holstein, Kiel University, Kiel, Germany.<br /><searchLink fieldCode="AU" term="%22Danese+S%22">Danese S</searchLink>; Humanitas University, Humanitas Research Hospital, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Feagan+B%22">Feagan B</searchLink>; Western University, Pomona, California and Alimentiv, Inc, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Pai+RK%22">Pai RK</searchLink>; Mayo Clinic Arizona, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Liu+DY%22">Liu DY</searchLink>; Protagonist Therapeutics, Inc, Newark, California.<br /><searchLink fieldCode="AU" term="%22Gupta+S%22">Gupta S</searchLink>; Protagonist Therapeutics, Inc, Newark, California. Electronic address: s.gupta@ptgx-inc.com.
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  Data: <searchLink fieldCode="JN" term="%220374630%22">Gastroenterology</searchLink> [Gastroenterology] 2021 Dec; Vol. 161 (6), pp. 1853-1864.e10. <i>Date of Electronic Publication: </i>2021 Aug 30.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22W%2EB%2E+Saunders%22">W.B. Saunders </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0374630 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1528-0012 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200165085%22">00165085 </searchLink><i>NLM ISO Abbreviation: </i>Gastroenterology <i>Subsets: </i>MEDLINE
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              Text: 2021 Dec
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