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Preparation, biological & cheminformatics-based assessment of N2,N4-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.

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Title: Preparation, biological & cheminformatics-based assessment of N2,N4-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.
Authors: Toviwek B; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand., Phuangsawai O; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand., Konsue A; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand., Hannongbua S; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand., Riley J; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Mutter N; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Anderson M; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Webster L; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Hallyburton I; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Read KD; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom., Gleeson MP; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand. Electronic address: paul.gl@kmitl.ac.th.
Source: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2021 Sep 15; Vol. 46, pp. 116348. Date of Electronic Publication: 2021 Aug 08.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Preparation, biological & cheminformatics-based assessment of N<superscript>2</superscript>,N<superscript>4</superscript>-diphenylpyrimidine-2,4-diamine as potential Kinase-targeted antimalarials.
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  Data: <searchLink fieldCode="AU" term="%22Toviwek+B%22">Toviwek B</searchLink>; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.<br /><searchLink fieldCode="AU" term="%22Phuangsawai+O%22">Phuangsawai O</searchLink>; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.<br /><searchLink fieldCode="AU" term="%22Konsue+A%22">Konsue A</searchLink>; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand.<br /><searchLink fieldCode="AU" term="%22Hannongbua+S%22">Hannongbua S</searchLink>; Department of Chemistry, Faculty of Science, Kasetsart University, Bangkok 10900, Thailand.<br /><searchLink fieldCode="AU" term="%22Riley+J%22">Riley J</searchLink>; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Mutter+N%22">Mutter N</searchLink>; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Anderson+M%22">Anderson M</searchLink>; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Webster+L%22">Webster L</searchLink>; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Hallyburton+I%22">Hallyburton I</searchLink>; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Read+KD%22">Read KD</searchLink>; Drug Discovery Unit, Divison of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gleeson+MP%22">Gleeson MP</searchLink>; Department of Biomedical Engineering, School of Engineering, King Mongkut's Institute of Technology Ladkrabang, Bangkok 10520, Thailand. Electronic address: paul.gl@kmitl.ac.th.
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  Data: <searchLink fieldCode="JN" term="%229413298%22">Bioorganic & medicinal chemistry</searchLink> [Bioorg Med Chem] 2021 Sep 15; Vol. 46, pp. 116348. <i>Date of Electronic Publication: </i>2021 Aug 08.
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