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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.

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Title: The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling.
Authors: Shen C; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; The Sheila and David Fuente Graduate Program in Cancer Biology, Miller School of Medicine, University of Miami, Miami, FL, USA., Nayak A; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Neitzel LR; Department of Medicine, University of Maryland, Baltimore, MD, USA., Adams AA; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Silver-Isenstadt M; Department of Medicine, University of Maryland, Baltimore, MD, USA., Sawyer LM; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Benchabane H; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Wang H; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Bunnag N; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Li B; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Wynn DT; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Yang F; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; The Sheila and David Fuente Graduate Program in Cancer Biology, Miller School of Medicine, University of Miami, Miami, FL, USA., Garcia-Contreras M; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA., Williams CH; Department of Medicine, University of Maryland, Baltimore, MD, USA., Dakshanamurthy S; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Hong CC; Department of Medicine, University of Maryland, Baltimore, MD, USA., Ayad NG; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.; Center for Therapeutic Innovation, Department of Neurological Surgery, Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Capobianco AJ; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA., Ahmed Y; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Lee E; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Robbins DJ; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA. dr956@georgetown.edu.; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. dr956@georgetown.edu.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA. dr956@georgetown.edu.
Source: Nature communications [Nat Commun] 2021 Sep 06; Vol. 12 (1), pp. 5263. Date of Electronic Publication: 2021 Sep 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Shen+C%22">Shen C</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; The Sheila and David Fuente Graduate Program in Cancer Biology, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Nayak+A%22">Nayak A</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Neitzel+LR%22">Neitzel LR</searchLink>; Department of Medicine, University of Maryland, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Adams+AA%22">Adams AA</searchLink>; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.<br /><searchLink fieldCode="AU" term="%22Silver-Isenstadt+M%22">Silver-Isenstadt M</searchLink>; Department of Medicine, University of Maryland, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Sawyer+LM%22">Sawyer LM</searchLink>; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Benchabane+H%22">Benchabane H</searchLink>; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.<br /><searchLink fieldCode="AU" term="%22Wang+H%22">Wang H</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Bunnag+N%22">Bunnag N</searchLink>; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.<br /><searchLink fieldCode="AU" term="%22Li+B%22">Li B</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Wynn+DT%22">Wynn DT</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Yang+F%22">Yang F</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; The Sheila and David Fuente Graduate Program in Cancer Biology, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Garcia-Contreras+M%22">Garcia-Contreras M</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Williams+CH%22">Williams CH</searchLink>; Department of Medicine, University of Maryland, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Dakshanamurthy+S%22">Dakshanamurthy S</searchLink>; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Hong+CC%22">Hong CC</searchLink>; Department of Medicine, University of Maryland, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Ayad+NG%22">Ayad NG</searchLink>; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA.; Center for Therapeutic Innovation, Department of Neurological Surgery, Miami Project to Cure Paralysis, Miller School of Medicine, University of Miami, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Capobianco+AJ%22">Capobianco AJ</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ahmed+Y%22">Ahmed Y</searchLink>; Department of Molecular and Systems Biology and the Norris Cotton Cancer Center, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.<br /><searchLink fieldCode="AU" term="%22Lee+E%22">Lee E</searchLink>; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Robbins+DJ%22">Robbins DJ</searchLink>; Molecular Oncology Program, The DeWitt Daughtry Family Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA. dr956@georgetown.edu.; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. dr956@georgetown.edu.; Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL, USA. dr956@georgetown.edu.
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