Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.

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Title: Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.
Authors: Lohoff T; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.; Epigenetics Programme, Babraham Institute, Cambridge, UK., Ghazanfar S; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK., Missarova A; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK., Koulena N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Pierson N; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Griffiths JA; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK.; Genomics Plc, Cambridge, UK., Bardot ES; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Eng CL; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA., Tyser RCV; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Argelaguet R; Epigenetics Programme, Babraham Institute, Cambridge, UK.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK., Guibentif C; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Sahlgrenska Center for Cancer Research, Department of Microbiology and Immunology, University of Gothenburg, Gothenburg, Sweden., Srinivas S; Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK., Briscoe J; The Francis Crick Institute, London, UK., Simons BD; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; The Wellcome/Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge, UK.; Department of Applied Mathematics and Theoretical Physics, Centre for Mathematical Sciences, University of Cambridge, Cambridge, UK., Hadjantonakis AK; Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Göttgens B; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Reik W; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. wolf.reik@babraham.ac.uk.; Epigenetics Programme, Babraham Institute, Cambridge, UK. wolf.reik@babraham.ac.uk.; Centre for Trophoblast Research, University of Cambridge, Cambridge, UK. wolf.reik@babraham.ac.uk.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. wolf.reik@babraham.ac.uk., Nichols J; Wellcome-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Cambridge, UK. jn270@cam.ac.uk.; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK. jn270@cam.ac.uk., Cai L; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, CA, USA. lcai@caltech.edu., Marioni JC; Cancer Research UK Cambridge Institute, University of Cambridge, Cambridge, UK. marioni@ebi.ac.uk.; European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK. marioni@ebi.ac.uk.; Wellcome Sanger Institute, Wellcome Genome Campus, Cambridge, UK. marioni@ebi.ac.uk.
Source: Nature biotechnology [Nat Biotechnol] 2022 Jan; Vol. 40 (1), pp. 74-85. Date of Electronic Publication: 2021 Sep 06.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1546-1696
DOI:10.1038/s41587-021-01006-2