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Development of an intracellular quantitative assay to measure compound binding kinetics.

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Title: Development of an intracellular quantitative assay to measure compound binding kinetics.
Authors: Lay CS; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Thomas DA; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK; Arctoris, Oxford OX14 4SA, UK., Evans JP; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Campbell M; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., McCombe K; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK; Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK., Phillipou AN; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Gordon LJ; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Jones EJ; Protein and Cellular Sciences, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Riching K; Promega Corporation, Madison, WI 53711, USA., Mahmood M; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Messenger C; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Carver CE; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Gatfield KM; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK., Craggs PD; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK; GSK-Francis Crick Institute Linklabs, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK. Electronic address: peter.d.craggs@gsk.com.
Source: Cell chemical biology [Cell Chem Biol] 2022 Feb 17; Vol. 29 (2), pp. 287-299.e8. Date of Electronic Publication: 2021 Sep 13.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101676030 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2451-9448 (Electronic) Linking ISSN: 24519448 NLM ISO Abbreviation: Cell Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of an intracellular quantitative assay to measure compound binding kinetics.
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  Data: <searchLink fieldCode="AU" term="%22Lay+CS%22">Lay CS</searchLink>; Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham NG7 2UH, UK; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+DA%22">Thomas DA</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK; Arctoris, Oxford OX14 4SA, UK.<br /><searchLink fieldCode="AU" term="%22Evans+JP%22">Evans JP</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Campbell+M%22">Campbell M</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22McCombe+K%22">McCombe K</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK; Patrick G. Johnston Centre for Cancer Research, School of Medicine, Dentistry and Biomedical Sciences, Queen's University Belfast, Belfast BT9 7AE, UK.<br /><searchLink fieldCode="AU" term="%22Phillipou+AN%22">Phillipou AN</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Gordon+LJ%22">Gordon LJ</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Jones+EJ%22">Jones EJ</searchLink>; Protein and Cellular Sciences, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Riching+K%22">Riching K</searchLink>; Promega Corporation, Madison, WI 53711, USA.<br /><searchLink fieldCode="AU" term="%22Mahmood+M%22">Mahmood M</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Messenger+C%22">Messenger C</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Carver+CE%22">Carver CE</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Gatfield+KM%22">Gatfield KM</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK.<br /><searchLink fieldCode="AU" term="%22Craggs+PD%22">Craggs PD</searchLink>; Medicine Design, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK; GSK-Francis Crick Institute Linklabs, Medicinal Science and Technology, GlaxoSmithKline, Stevenage SG1 2NY, UK. Electronic address: peter.d.craggs@gsk.com.
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              Text: 2022 Feb 17
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