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NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons.

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Title: NRXN1α+/- is associated with increased excitability in ASD iPSC-derived neurons.
Authors: Avazzadeh S; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland., Quinlan LR; Physiology and Cellular Physiology Research Laboratory, School of Medicine, CÚRAM SFI Centre for Research in Medical Devices, National University of Ireland (NUI), Galway, Ireland., Reilly J; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland., McDonagh K; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland., Jalali A; School of Mathematical Sciences, University College Cork, Cork, Ireland., Wang Y; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.; Department of Physiology, College of Life Science, Hebei Normal University, Shijiazhuang, China., McInerney V; HRB Clinical Research Facility, National University of Ireland (NUI), Galway, Ireland., Krawczyk J; Department of Haematology, Galway University Hospital, Galway, Ireland., Ding Y; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland., Fitzgerald J; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., O'Sullivan M; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland., Forman EB; Children's University Hospital, Temple Street, Dublin, Ireland., Lynch SA; Children's University Hospital, Temple Street, Dublin, Ireland.; Department of Clinical Genetics, OLCHC, Dublin 12, Ireland., Ennis S; School of Medicine and Medical Science, UCD Academic Centre On Rare Diseases, University College Dublin, Dublin, Ireland., Feerick N; Centre for Bioengineering, Trinity College Institute of Neuroscience, School of Medicine, School of Engineering, Trinity College Dublin, Dublin, Ireland., Reilly R; Centre for Bioengineering, Trinity College Institute of Neuroscience, School of Medicine, School of Engineering, Trinity College Dublin, Dublin, Ireland., Li W; Bio-X Institutes, Key Laboratory for the Genetics of Development and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, China., Shen X; School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, China., Yang G; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China., Lu Y; College of Pharmacy, Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, China., Peeters H; Centre for Human Genetics, University Hospital Leuven, KU Leuven, 3000, Leuven, Belgium., Dockery P; Centre for Microscopy and Imaging, Anatomy, School of Medicine, National University of Ireland (NUI), Galway, Ireland., O'Brien T; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland., Shen S; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland. sanbing.shen@nuigalway.ie.; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, D02, Ireland. sanbing.shen@nuigalway.ie., Gallagher L; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
Source: BMC neuroscience [BMC Neurosci] 2021 Sep 15; Vol. 22 (1), pp. 56. Date of Electronic Publication: 2021 Sep 15.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 100966986 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2202 (Electronic) Linking ISSN: 14712202 NLM ISO Abbreviation: BMC Neurosci Subsets: MEDLINE
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  Data: NRXN1α<superscript>+/-</superscript> is associated with increased excitability in ASD iPSC-derived neurons.
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  Data: <searchLink fieldCode="AU" term="%22Avazzadeh+S%22">Avazzadeh S</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.<br /><searchLink fieldCode="AU" term="%22Quinlan+LR%22">Quinlan LR</searchLink>; Physiology and Cellular Physiology Research Laboratory, School of Medicine, CÚRAM SFI Centre for Research in Medical Devices, National University of Ireland (NUI), Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Reilly+J%22">Reilly J</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.<br /><searchLink fieldCode="AU" term="%22McDonagh+K%22">McDonagh K</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.<br /><searchLink fieldCode="AU" term="%22Jalali+A%22">Jalali A</searchLink>; School of Mathematical Sciences, University College Cork, Cork, Ireland.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.; Department of Physiology, College of Life Science, Hebei Normal University, Shijiazhuang, China.<br /><searchLink fieldCode="AU" term="%22McInerney+V%22">McInerney V</searchLink>; HRB Clinical Research Facility, National University of Ireland (NUI), Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Krawczyk+J%22">Krawczyk J</searchLink>; Department of Haematology, Galway University Hospital, Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22Ding+Y%22">Ding Y</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.<br /><searchLink fieldCode="AU" term="%22Fitzgerald+J%22">Fitzgerald J</searchLink>; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Sullivan+M%22">O'Sullivan M</searchLink>; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Forman+EB%22">Forman EB</searchLink>; Children's University Hospital, Temple Street, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Lynch+SA%22">Lynch SA</searchLink>; Children's University Hospital, Temple Street, Dublin, Ireland.; Department of Clinical Genetics, OLCHC, Dublin 12, Ireland.<br /><searchLink fieldCode="AU" term="%22Ennis+S%22">Ennis S</searchLink>; School of Medicine and Medical Science, UCD Academic Centre On Rare Diseases, University College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Feerick+N%22">Feerick N</searchLink>; Centre for Bioengineering, Trinity College Institute of Neuroscience, School of Medicine, School of Engineering, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Reilly+R%22">Reilly R</searchLink>; Centre for Bioengineering, Trinity College Institute of Neuroscience, School of Medicine, School of Engineering, Trinity College Dublin, Dublin, Ireland.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Bio-X Institutes, Key Laboratory for the Genetics of Development and Neuropsychiatric Disorders (Ministry of Education), Shanghai Key Laboratory of Psychotic Disorders, and Brain Science and Technology Research Center, Shanghai Jiao Tong University, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Shen+X%22">Shen X</searchLink>; School of Medicine and Life Sciences, Nanjing University of Chinese Medicine, 138 Xianlin Road, Nanjing, 210023, China.<br /><searchLink fieldCode="AU" term="%22Yang+G%22">Yang G</searchLink>; College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Lu+Y%22">Lu Y</searchLink>; College of Pharmacy, Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica, Jiangsu Collaborative Innovation Center of Traditional Chinese Medicine (TCM) Prevention and Treatment of Tumor, Nanjing University of Chinese Medicine, Nanjing, 210023, Jiangsu, China.<br /><searchLink fieldCode="AU" term="%22Peeters+H%22">Peeters H</searchLink>; Centre for Human Genetics, University Hospital Leuven, KU Leuven, 3000, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Dockery+P%22">Dockery P</searchLink>; Centre for Microscopy and Imaging, Anatomy, School of Medicine, National University of Ireland (NUI), Galway, Ireland.<br /><searchLink fieldCode="AU" term="%22O'Brien+T%22">O'Brien T</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland.<br /><searchLink fieldCode="AU" term="%22Shen+S%22">Shen S</searchLink>; School of Medicine, Regenerative Medicine Institute, Biomedical Science Building BMS-1021, National University of Ireland Galway, Dangan, Ireland. sanbing.shen@nuigalway.ie.; FutureNeuro Research Centre, Royal College of Surgeons in Ireland, Dublin, D02, Ireland. sanbing.shen@nuigalway.ie.<br /><searchLink fieldCode="AU" term="%22Gallagher+L%22">Gallagher L</searchLink>; Trinity Institute of Neuroscience, Trinity College Dublin, Dublin, Ireland.
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  Data: <searchLink fieldCode="JN" term="%22100966986%22">BMC neuroscience</searchLink> [BMC Neurosci] 2021 Sep 15; Vol. 22 (1), pp. 56. <i>Date of Electronic Publication: </i>2021 Sep 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>100966986 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1471-2202 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214712202%22">14712202 </searchLink><i>NLM ISO Abbreviation: </i>BMC Neurosci <i>Subsets: </i>MEDLINE
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