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Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis.

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Title: Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis.
Authors: Elborn JS; Faculty of Medicine Health and Life sciences Queens University School of Medicine, Belfast, UK., Konstan MW; Department of Pediatrics, Case Western Reserve University School of Medicine and Rainbow Babies & Children's Hospital, Cleveland, OH, USA., Taylor-Cousar JL; Departments of Medicine and Pediatrics, National Jewish Health, Denver, CO, USA., Fajac I; Physiology Department, Cochin Hospital, APHP Centre, Paris, France; Université de Paris, Paris, France., Horsley A; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Sutharsan S; Division of Cystic Fibrosis, Department of Pulmonary Medicine, University Medicine EssenRuhrlandklinik, University of DuisburgEssen, Essen, Germany., Aaron SD; Ottawa Health Research Institute, Ottawa, Ontario, Canada., Daines CL; Department of Pediatrics, University of Arizona, Tucson, AZ, USA., Uluer A; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Downey DG; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK., Lucidi VV; Cystic Fibrosis Center, Children's Hospital and Research Institute, Bambino Gesu, Rome, Italy., Ahuja S; Celtaxsys, Inc., Atlanta, GA, USA., Springman E; Celtaxsys, Inc., Atlanta, GA, USA., Mershon J; Celtaxsys, Inc., Atlanta, GA, USA., Grosswald R; Celtaxsys, Inc., Atlanta, GA, USA., Rowe SM; Gregory Fleming James Cystic Fibrosis Research Center and Department of Medicine, University of Alabama at Birmingham, 1918 University Blvd, MCLM 804, Birmingham 35294, AL, USA. Electronic address: smrowe@uab.edu.
Corporate Authors: EMPIRE-CF study group
Source: Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society [J Cyst Fibros] 2021 Nov; Vol. 20 (6), pp. 1026-1034. Date of Electronic Publication: 2021 Sep 17.
Publication Type: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101128966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-5010 (Electronic) Linking ISSN: 15691993 NLM ISO Abbreviation: J Cyst Fibros Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Empire-CF study: A phase 2 clinical trial of leukotriene A4 hydrolase inhibitor acebilustat in adult subjects with cystic fibrosis.
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  Data: <searchLink fieldCode="AU" term="%22Elborn+JS%22">Elborn JS</searchLink>; Faculty of Medicine Health and Life sciences Queens University School of Medicine, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Konstan+MW%22">Konstan MW</searchLink>; Department of Pediatrics, Case Western Reserve University School of Medicine and Rainbow Babies & Children's Hospital, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Taylor-Cousar+JL%22">Taylor-Cousar JL</searchLink>; Departments of Medicine and Pediatrics, National Jewish Health, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Fajac+I%22">Fajac I</searchLink>; Physiology Department, Cochin Hospital, APHP Centre, Paris, France; Université de Paris, Paris, France.<br /><searchLink fieldCode="AU" term="%22Horsley+A%22">Horsley A</searchLink>; Division of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Sutharsan+S%22">Sutharsan S</searchLink>; Division of Cystic Fibrosis, Department of Pulmonary Medicine, University Medicine EssenRuhrlandklinik, University of DuisburgEssen, Essen, Germany.<br /><searchLink fieldCode="AU" term="%22Aaron+SD%22">Aaron SD</searchLink>; Ottawa Health Research Institute, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Daines+CL%22">Daines CL</searchLink>; Department of Pediatrics, University of Arizona, Tucson, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Uluer+A%22">Uluer A</searchLink>; Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Downey+DG%22">Downey DG</searchLink>; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.<br /><searchLink fieldCode="AU" term="%22Lucidi+VV%22">Lucidi VV</searchLink>; Cystic Fibrosis Center, Children's Hospital and Research Institute, Bambino Gesu, Rome, Italy.<br /><searchLink fieldCode="AU" term="%22Ahuja+S%22">Ahuja S</searchLink>; Celtaxsys, Inc., Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Springman+E%22">Springman E</searchLink>; Celtaxsys, Inc., Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Mershon+J%22">Mershon J</searchLink>; Celtaxsys, Inc., Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Grosswald+R%22">Grosswald R</searchLink>; Celtaxsys, Inc., Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Rowe+SM%22">Rowe SM</searchLink>; Gregory Fleming James Cystic Fibrosis Research Center and Department of Medicine, University of Alabama at Birmingham, 1918 University Blvd, MCLM 804, Birmingham 35294, AL, USA. Electronic address: smrowe@uab.edu.
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  Data: <searchLink fieldCode="JN" term="%22101128966%22">Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society</searchLink> [J Cyst Fibros] 2021 Nov; Vol. 20 (6), pp. 1026-1034. <i>Date of Electronic Publication: </i>2021 Sep 17.
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  Data: Clinical Trial, Phase II; Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101128966 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-5010 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2215691993%22">15691993 </searchLink><i>NLM ISO Abbreviation: </i>J Cyst Fibros <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.jcf.2021.08.007
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              Text: 2021 Nov
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