Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression. - Yun H; Narayan N; Vohra S; Giotopoulos G; Mupo A; Madrigal P; Sasca D; Lara-Astiaso D; Horton SJ; Agrawal-Singh S; Meduri E; Basheer F; et al. (Nature genetics, 2021)