Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs. - Johannes JW; Balazs A; Barratt D; Bista M; Chuba MD; Cosulich S; Critchlow SE; Degorce SL; Di Fruscia P; Edmondson SD; Embrey K; Fawell S; et al. (Journal of medicinal chemistry, 2021)