Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk.
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| Title: | Transcriptome-based polygenic score links depression-related corticolimbic gene expression changes to sex-specific brain morphology and depression risk. |
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| Authors: | Miles AE; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada., Dos Santos FC; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada., Byrne EM; Institute for Molecular Bioscience, The University of Queensland, Brisbane, QLD, Australia., Renteria ME; Department of Genetics & Computational Biology, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, QLD, Australia., McIntosh AM; Division of Psychiatry, University of Edinburgh, Edinburgh, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Adams MJ; Division of Psychiatry, University of Edinburgh, Edinburgh, UK., Pistis G; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Castelao E; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Preisig M; Department of Psychiatry, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland., Baune BT; Department of Psychiatry, University of Münster, Münster, Nordrhein-Westfalen, Germany.; Department of Psychiatry, Melbourne Medical School, University of Melbourne, Melbourne, Australia.; Florey Institute for Neuroscience and Mental Health, University of Melbourne, Melbourne, Australia., Schubert KO; Department of Psychiatry, University of Adelaide, Adelaide, Australia.; Northern Adelaide Mental Health Services, SA Health, Salisbury, Australia., Lewis CM; Social, Genetic and Developmental Psychiatry Centre, King's College London, London, UK.; Department of Medical & Molecular Genetics, King's College London, London, UK., Jones LA; Department of Psychological Medicine, University of Worcester, Worcester, UK., Jones I; MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff, UK., Uher R; Department of Psychiatry, Dalhousie University, Halifax, NS, Canada., Smoller JW; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit (PNGU), Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Perlis RH; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Levinson DF; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA., Potash JB; Department of Psychiatry and Behavioral Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA., Weissman MM; Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY, USA.; Division of Translational Epidemiology, New York State Psychiatric Institute, New York, NY, USA., Shi J; Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA., Lewis G; Division of Psychiatry, University College London, Faculty of Brain Sciences, London, UK., Penninx BWJH; Department of Psychiatry, Vrije Universiteit Medical Center and GGZ inGeest, Amsterdam, Netherlands., Boomsma DI; Department of Biological Psychology & EMGO+ Institute for Health and Care Research, Vrije Universiteit Amsterdam, Amsterdam, Netherlands., Hamilton SP; Department of Psychiatry, Kaiser Permanente Northern California, San Francisco, CA, USA., Sibille E; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada., Hariri AR; Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC, USA., Nikolova YS; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada. yuliya.nikolova@camh.ca.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. yuliya.nikolova@camh.ca. |
| Corporate Authors: | Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium |
| Source: | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology [Neuropsychopharmacology] 2021 Dec; Vol. 46 (13), pp. 2304-2311. Date of Electronic Publication: 2021 Sep 29. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8904907 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-634X (Electronic) Linking ISSN: 0893133X NLM ISO Abbreviation: Neuropsychopharmacology Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34588609 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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Department of Psychiatry, Kaiser Permanente Northern California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sibille+E%22">Sibille E</searchLink>; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada.; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Hariri+AR%22">Hariri AR</searchLink>; Laboratory of NeuroGenetics, Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.<br /><searchLink fieldCode="AU" term="%22Nikolova+YS%22">Nikolova YS</searchLink>; Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), Toronto, ON, Canada. yuliya.nikolova@camh.ca.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada. yuliya.nikolova@camh.ca. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Major+Depressive+Disorder+Working+Group+of+the+Psychiatric+Genomics+Consortium%22">Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228904907%22">Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology</searchLink> [Neuropsychopharmacology] 2021 Dec; Vol. 46 (13), pp. 2304-2311. <i>Date of Electronic Publication: </i>2021 Sep 29. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8904907 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1740-634X (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220893133X%22">0893133X </searchLink><i>NLM ISO Abbreviation: </i>Neuropsychopharmacology <i>Subsets: </i>MEDLINE |
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