Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN response.
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| Title: | Modulation of SF3B1 in the pre-mRNA spliceosome induces a RIG-I-dependent type I IFN response. |
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| Authors: | Chang AY; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA., Zhou YJ; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA., Iyengar S; Emerging Science & Innovation, Pfizer Inc, Pearl River, New York, USA., Pobiarzyn PW; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA., Tishchenko P; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA., Shah KM; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA., Wheeler H; Medicine Design, Worldwide Research & Development, Pfizer Inc, Groton, Connecticut, USA., Wang YM; Medicine Design, Worldwide Research & Development, Pfizer Inc, Groton, Connecticut, USA., Loria PM; Medicine Design, Worldwide Research & Development, Pfizer Inc, Groton, Connecticut, USA., Loganzo F; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA., Woo SR; Oncology Research & Development, Pfizer Inc, Pearl River, New York, USA. Electronic address: realwoomir@gmail.com. |
| Source: | The Journal of biological chemistry [J Biol Chem] 2021 Nov; Vol. 297 (5), pp. 101277. Date of Electronic Publication: 2021 Oct 05. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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