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Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.

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Title: Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.
Authors: Searle AK; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia., Chen YC; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia., Wallert M; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia., McFadyen JD; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.; Clinical Haematology, Alfred Hospital, Melbourne, Australia., Maluenda AC; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia., Noonan J; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia., Kanellakis P; Atherosclerosis and Cell Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia., Zaldivia MTK; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia., Huang A; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia., Lioe H; CSL Limited, Bio21 Institute, Parkville, Melbourne, Australia., Biondo M; CSL Limited, Bio21 Institute, Parkville, Melbourne, Australia., Nolte MW; CSL Behring Innovation GmbH, Marburg, Germany., Rossato P; CSL Behring Innovation GmbH, Marburg, Germany., Bobik A; Department of Medicine, Monash University, Melbourne, Australia.; Atherosclerosis and Cell Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Immunology, Monash University, Melbourne, Australia., Panousis C; CSL Limited, Bio21 Institute, Parkville, Melbourne, Australia., Wang X; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia., Hosseini H; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia., Peter K; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.; Department of Immunology, Monash University, Melbourne, Australia.; Department of Cardiology, Alfred Hospital, Melbourne, Australia.
Source: Thrombosis and haemostasis [Thromb Haemost] 2022 Feb; Vol. 122 (2), pp. 196-207. Date of Electronic Publication: 2022 Jan 21.
Publication Type: Journal Article
Journal Info: Publisher: Thieme Country of Publication: Germany NLM ID: 7608063 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2567-689X (Electronic) Linking ISSN: 03406245 NLM ISO Abbreviation: Thromb Haemost Subsets: MEDLINE
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  Data: Pharmacological Inhibition of Factor XIIa Attenuates Abdominal Aortic Aneurysm, Reduces Atherosclerosis, and Stabilizes Atherosclerotic Plaques.
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  Data: <searchLink fieldCode="AU" term="%22Searle+AK%22">Searle AK</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Chen+YC%22">Chen YC</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Wallert+M%22">Wallert M</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22McFadyen+JD%22">McFadyen JD</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.; Clinical Haematology, Alfred Hospital, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Maluenda+AC%22">Maluenda AC</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Noonan+J%22">Noonan J</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Kanellakis+P%22">Kanellakis P</searchLink>; Atherosclerosis and Cell Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Zaldivia+MTK%22">Zaldivia MTK</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+A%22">Huang A</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Lioe+H%22">Lioe H</searchLink>; CSL Limited, Bio21 Institute, Parkville, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Biondo+M%22">Biondo M</searchLink>; CSL Limited, Bio21 Institute, Parkville, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Nolte+MW%22">Nolte MW</searchLink>; CSL Behring Innovation GmbH, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Rossato+P%22">Rossato P</searchLink>; CSL Behring Innovation GmbH, Marburg, Germany.<br /><searchLink fieldCode="AU" term="%22Bobik+A%22">Bobik A</searchLink>; Department of Medicine, Monash University, Melbourne, Australia.; Atherosclerosis and Cell Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Immunology, Monash University, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Panousis+C%22">Panousis C</searchLink>; CSL Limited, Bio21 Institute, Parkville, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Hosseini+H%22">Hosseini H</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Peter+K%22">Peter K</searchLink>; Atherothrombosis and Vascular Biology Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.; Department of Medicine, Monash University, Melbourne, Australia.; Department of Cardiometabolic Health, University of Melbourne, Melbourne, Australia.; Department of Immunology, Monash University, Melbourne, Australia.; Department of Cardiology, Alfred Hospital, Melbourne, Australia.
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  Data: <searchLink fieldCode="JN" term="%227608063%22">Thrombosis and haemostasis</searchLink> [Thromb Haemost] 2022 Feb; Vol. 122 (2), pp. 196-207. <i>Date of Electronic Publication: </i>2022 Jan 21.
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