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An open-label phase I dose-escalation study of the safety and pharmacokinetics of DMUC4064A in patients with platinum-resistant ovarian cancer.

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Title: An open-label phase I dose-escalation study of the safety and pharmacokinetics of DMUC4064A in patients with platinum-resistant ovarian cancer.
Authors: Liu J; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address: joyce_liu@dfci.harvard.edu., Burris H; Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN, USA., Wang JS; Hematologic Oncology, Florida Cancer Specialists/Sarah Cannon Research Institute, Sarasota, FL, USA., Barroilhet L; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, USA., Gutierrez M; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA., Wang Y; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA., Vaze A; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA., Commerford R; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA., Royer-Joo S; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA., Choeurng V; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA., Humke E; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA., Moore K; University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
Source: Gynecologic oncology [Gynecol Oncol] 2021 Dec; Vol. 163 (3), pp. 473-480. Date of Electronic Publication: 2021 Oct 06.
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: An open-label phase I dose-escalation study of the safety and pharmacokinetics of DMUC4064A in patients with platinum-resistant ovarian cancer.
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  Data: <searchLink fieldCode="AU" term="%22Liu+J%22">Liu J</searchLink>; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA. Electronic address: joyce_liu@dfci.harvard.edu.<br /><searchLink fieldCode="AU" term="%22Burris+H%22">Burris H</searchLink>; Sarah Cannon Research Institute and Tennessee Oncology, Nashville, TN, USA.<br /><searchLink fieldCode="AU" term="%22Wang+JS%22">Wang JS</searchLink>; Hematologic Oncology, Florida Cancer Specialists/Sarah Cannon Research Institute, Sarasota, FL, USA.<br /><searchLink fieldCode="AU" term="%22Barroilhet+L%22">Barroilhet L</searchLink>; Department of Obstetrics and Gynecology, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22Gutierrez+M%22">Gutierrez M</searchLink>; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Vaze+A%22">Vaze A</searchLink>; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Commerford+R%22">Commerford R</searchLink>; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Royer-Joo+S%22">Royer-Joo S</searchLink>; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Choeurng+V%22">Choeurng V</searchLink>; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Humke+E%22">Humke E</searchLink>; Early Clinical Development, Genentech, Inc, South San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Moore+K%22">Moore K</searchLink>; University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA.
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  Data: <searchLink fieldCode="JN" term="%220365304%22">Gynecologic oncology</searchLink> [Gynecol Oncol] 2021 Dec; Vol. 163 (3), pp. 473-480. <i>Date of Electronic Publication: </i>2021 Oct 06.
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  Data: Clinical Trial, Phase I; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0365304 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-6859 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200908258%22">00908258 </searchLink><i>NLM ISO Abbreviation: </i>Gynecol Oncol <i>Subsets: </i>MEDLINE
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              Text: 2021 Dec
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