Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.

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Title: Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
Authors: Villiger L; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Schmidheini L; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Mathis N; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Rothgangl T; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Marquart K; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Schwank G; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.
Source: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Aug 26; Vol. 26, pp. 502-510. Date of Electronic Publication: 2021 Aug 26 (Print Publication: 2021).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Villiger+L%22">Villiger L</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schmidheini+L%22">Schmidheini L</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mathis+N%22">Mathis N</searchLink>; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rothgangl+T%22">Rothgangl T</searchLink>; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marquart+K%22">Marquart K</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schwank+G%22">Schwank G</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101581621%22">Molecular therapy. Nucleic acids</searchLink> [Mol Ther Nucleic Acids] 2021 Aug 26; Vol. 26, pp. 502-510. <i>Date of Electronic Publication: </i>2021 Aug 26 (<i>Print Publication: </i>2021).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101581621 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2162-2531 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221622531%22">21622531 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Nucleic Acids <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.omtn.2021.08.025
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              Text: 2021 Aug 26
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