Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope.
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| Title: | Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope. |
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| Authors: | Villiger L; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Schmidheini L; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Mathis N; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Rothgangl T; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Marquart K; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland., Schwank G; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland. |
| Source: | Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Aug 26; Vol. 26, pp. 502-510. Date of Electronic Publication: 2021 Aug 26 (Print Publication: 2021). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34631280 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Villiger+L%22">Villiger L</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schmidheini+L%22">Schmidheini L</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mathis+N%22">Mathis N</searchLink>; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rothgangl+T%22">Rothgangl T</searchLink>; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Marquart+K%22">Marquart K</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schwank+G%22">Schwank G</searchLink>; Department of Biology, ETH Zurich, Institute for Molecular Health Sciences, Zurich, Switzerland.; University of Zurich, Institute of Pharmacology and Toxicology, Zurich, Switzerland. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101581621%22">Molecular therapy. Nucleic acids</searchLink> [Mol Ther Nucleic Acids] 2021 Aug 26; Vol. 26, pp. 502-510. <i>Date of Electronic Publication: </i>2021 Aug 26 (<i>Print Publication: </i>2021). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101581621 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Print <i>ISSN: </i>2162-2531 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2221622531%22">21622531 </searchLink><i>NLM ISO Abbreviation: </i>Mol Ther Nucleic Acids <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34631280 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.omtn.2021.08.025 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 502 Titles: – TitleFull: Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Villiger L – PersonEntity: Name: NameFull: Schmidheini L – PersonEntity: Name: NameFull: Mathis N – PersonEntity: Name: NameFull: Rothgangl T – PersonEntity: Name: NameFull: Marquart K – PersonEntity: Name: NameFull: Schwank G IsPartOfRelationships: – BibEntity: Dates: – D: 26 M: 08 Text: 2021 Aug 26 Type: published Y: 2021 Identifiers: – Type: issn-print Value: 2162-2531 Numbering: – Type: volume Value: 26 Titles: – TitleFull: Molecular therapy. Nucleic acids Type: main |
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