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Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.

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Title: Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
Authors: Sheng T; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore., Ho SWT; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore., Ooi WF; Epigenetic and Epitranscriptomic Regulation, Genome Institute of Singapore, Singapore, 138672, Singapore., Xu C; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore., Xing M; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Epigenetic and Epitranscriptomic Regulation, Genome Institute of Singapore, Singapore, 138672, Singapore., Padmanabhan N; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore., Huang KK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore., Ma L; The Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA., Ray M; The Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA., Guo YA; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore., Sim NL; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore., Anene-Nzelu CG; Cardiovascular Research Institute, National University Health System, Singapore, 119074, Singapore.; Precision Medicine and Population Genomics (Germline), Genome Institute of Singapore, Singapore, Singapore.; Montreal Heart Institute, Montreal, Canada.; Department of Medicine, University of Montreal, Montreal, Canada., Chang MM; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore., Razavi-Mohseni M; Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, USA., Beer MA; Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, USA., Foo RSY; Cardiovascular Research Institute, National University Health System, Singapore, 119074, Singapore.; Precision Medicine and Population Genomics (Germline), Genome Institute of Singapore, Singapore, Singapore., Sundar R; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Hospital, Singapore, 119074, Singapore., Chan YH; Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore., Tan ALK; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore., Ong X; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore., Skanderup AJ; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore., White KP; The Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA. kevin@tempus.com.; Tempus Labs, Chicago, USA. kevin@tempus.com., Jha S; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore. csisjha@nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore. csisjha@nus.edu.sg.; NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. csisjha@nus.edu.sg.; Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA. csisjha@nus.edu.sg., Tan P; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore. gmstanp@duke-nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore. gmstanp@duke-nus.edu.sg.; Epigenetic and Epitranscriptomic Regulation, Genome Institute of Singapore, Singapore, 138672, Singapore. gmstanp@duke-nus.edu.sg.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre Singapore, Singapore, 168752, Singapore. gmstanp@duke-nus.edu.sg.; Department of Physiology, National University of Singapore, Singapore, 117593, Singapore. gmstanp@duke-nus.edu.sg.; Singapore Gastric Cancer Consortium, Singapore, 119228, Singapore. gmstanp@duke-nus.edu.sg.
Source: Genome medicine [Genome Med] 2021 Oct 11; Vol. 13 (1), pp. 158. Date of Electronic Publication: 2021 Oct 11.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101475844 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-994X (Electronic) Linking ISSN: 1756994X NLM ISO Abbreviation: Genome Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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DbLabel: MEDLINE Ultimate
An: 34635154
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  Data: Integrative epigenomic and high-throughput functional enhancer profiling reveals determinants of enhancer heterogeneity in gastric cancer.
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  Data: <searchLink fieldCode="AU" term="%22Sheng+T%22">Sheng T</searchLink>; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore.; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Ho+SWT%22">Ho SWT</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Ooi+WF%22">Ooi WF</searchLink>; Epigenetic and Epitranscriptomic Regulation, Genome Institute of Singapore, Singapore, 138672, Singapore.<br /><searchLink fieldCode="AU" term="%22Xu+C%22">Xu C</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore.<br /><searchLink fieldCode="AU" term="%22Xing+M%22">Xing M</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Epigenetic and Epitranscriptomic Regulation, Genome Institute of Singapore, Singapore, 138672, Singapore.<br /><searchLink fieldCode="AU" term="%22Padmanabhan+N%22">Padmanabhan N</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Huang+KK%22">Huang KK</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Ma+L%22">Ma L</searchLink>; The Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Ray+M%22">Ray M</searchLink>; The Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA.<br /><searchLink fieldCode="AU" term="%22Guo+YA%22">Guo YA</searchLink>; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore.<br /><searchLink fieldCode="AU" term="%22Sim+NL%22">Sim NL</searchLink>; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore.<br /><searchLink fieldCode="AU" term="%22Anene-Nzelu+CG%22">Anene-Nzelu CG</searchLink>; Cardiovascular Research Institute, National University Health System, Singapore, 119074, Singapore.; Precision Medicine and Population Genomics (Germline), Genome Institute of Singapore, Singapore, Singapore.; Montreal Heart Institute, Montreal, Canada.; Department of Medicine, University of Montreal, Montreal, Canada.<br /><searchLink fieldCode="AU" term="%22Chang+MM%22">Chang MM</searchLink>; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore.<br /><searchLink fieldCode="AU" term="%22Razavi-Mohseni+M%22">Razavi-Mohseni M</searchLink>; Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, USA.<br /><searchLink fieldCode="AU" term="%22Beer+MA%22">Beer MA</searchLink>; Department of Biomedical Engineering and McKusick-Nathans Department of Genetic Medicine, Johns Hopkins University, Baltimore, USA.<br /><searchLink fieldCode="AU" term="%22Foo+RSY%22">Foo RSY</searchLink>; Cardiovascular Research Institute, National University Health System, Singapore, 119074, Singapore.; Precision Medicine and Population Genomics (Germline), Genome Institute of Singapore, Singapore, Singapore.<br /><searchLink fieldCode="AU" term="%22Sundar+R%22">Sundar R</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.; Department of Haematology-Oncology, National University Cancer Institute Singapore, National University Hospital, Singapore, 119074, Singapore.<br /><searchLink fieldCode="AU" term="%22Chan+YH%22">Chan YH</searchLink>; Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 119228, Singapore.<br /><searchLink fieldCode="AU" term="%22Tan+ALK%22">Tan ALK</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Ong+X%22">Ong X</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore.<br /><searchLink fieldCode="AU" term="%22Skanderup+AJ%22">Skanderup AJ</searchLink>; Precision Medicine and Population Genomics (Somatic), Genome Institute of Singapore, Singapore, 138672, Singapore.<br /><searchLink fieldCode="AU" term="%22White+KP%22">White KP</searchLink>; The Institute for Genomics and Systems Biology, The University of Chicago, Chicago, Illinois, USA. kevin@tempus.com.; Tempus Labs, Chicago, USA. kevin@tempus.com.<br /><searchLink fieldCode="AU" term="%22Jha+S%22">Jha S</searchLink>; Department of Biochemistry, National University of Singapore, Singapore, 117596, Singapore. csisjha@nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore. csisjha@nus.edu.sg.; NUS Center for Cancer Research, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117599, Singapore. csisjha@nus.edu.sg.; Department of Physiological Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK, USA. csisjha@nus.edu.sg.<br /><searchLink fieldCode="AU" term="%22Tan+P%22">Tan P</searchLink>; Cancer and Stem Cell Biology Program, Duke-NUS Medical School, Singapore, 169857, Singapore. gmstanp@duke-nus.edu.sg.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 117599, Singapore. gmstanp@duke-nus.edu.sg.; Epigenetic and Epitranscriptomic Regulation, Genome Institute of Singapore, Singapore, 138672, Singapore. gmstanp@duke-nus.edu.sg.; SingHealth/Duke-NUS Institute of Precision Medicine, National Heart Centre Singapore, Singapore, 168752, Singapore. gmstanp@duke-nus.edu.sg.; Department of Physiology, National University of Singapore, Singapore, 117593, Singapore. gmstanp@duke-nus.edu.sg.; Singapore Gastric Cancer Consortium, Singapore, 119228, Singapore. gmstanp@duke-nus.edu.sg.
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  Data: <searchLink fieldCode="JN" term="%22101475844%22">Genome medicine</searchLink> [Genome Med] 2021 Oct 11; Vol. 13 (1), pp. 158. <i>Date of Electronic Publication: </i>2021 Oct 11.
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