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Sustained Efficacy and Safety of Burosumab, a Monoclonal Antibody to FGF23, in Children With X-Linked Hypophosphatemia.

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Title: Sustained Efficacy and Safety of Burosumab, a Monoclonal Antibody to FGF23, in Children With X-Linked Hypophosphatemia.
Authors: Linglart A; AP-HP, Endocrinology and Diabetes for Children, Reference Center for Rare Disorders of the Calcium and Phosphate Metabolism, and Filière OSCAR, Bicêtre Paris Saclay Hospital, Le Kremlin-Bicêtre, France.; Paris-Saclay University, INSERM 1189, Le Kremlin-Bicêtre, France., Imel EA; Indiana University School of Medicine, Indianapolis, IN, USA., Whyte MP; Shriners Hospitals for Children - St. Louis, MO, USA.; Division of Bone and Mineral Diseases, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA., Portale AA; University of California, San Francisco, CA, USA., Högler W; Johannes Kepler University Linz, Linz, Austria.; University of Birmingham, Birmingham, UK., Boot AM; University Medical Center Groningen, University of Groningen, Groningen, the Netherlands., Padidela R; Royal Manchester Children's Hospital and Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK., Van't Hoff W; Great Ormond Street Hospital, London, UK., Gottesman GS; Shriners Hospitals for Children - St. Louis, St Louis, MO, USA., Chen A; Ultragenyx Pharmaceutical Inc., Novato, CA, USA., Skrinar A; Ultragenyx Pharmaceutical Inc., Novato, CA, USA., Scott Roberts M; Ultragenyx Pharmaceutical Inc., Novato, CA, USA., Carpenter TO; Yale University School of Medicine, New Haven, CT, USA.
Source: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2022 Feb 17; Vol. 107 (3), pp. 813-824.
Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0375362 Publication Model: Print Cited Medium: Internet ISSN: 1945-7197 (Electronic) Linking ISSN: 0021972X NLM ISO Abbreviation: J Clin Endocrinol Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Sustained Efficacy and Safety of Burosumab, a Monoclonal Antibody to FGF23, in Children With X-Linked Hypophosphatemia.
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  Data: <searchLink fieldCode="AU" term="%22Linglart+A%22">Linglart A</searchLink>; AP-HP, Endocrinology and Diabetes for Children, Reference Center for Rare Disorders of the Calcium and Phosphate Metabolism, and Filière OSCAR, Bicêtre Paris Saclay Hospital, Le Kremlin-Bicêtre, France.; Paris-Saclay University, INSERM 1189, Le Kremlin-Bicêtre, France.<br /><searchLink fieldCode="AU" term="%22Imel+EA%22">Imel EA</searchLink>; Indiana University School of Medicine, Indianapolis, IN, USA.<br /><searchLink fieldCode="AU" term="%22Whyte+MP%22">Whyte MP</searchLink>; Shriners Hospitals for Children - St. Louis, MO, USA.; Division of Bone and Mineral Diseases, Department of Internal Medicine, Washington University School of Medicine, St. Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Portale+AA%22">Portale AA</searchLink>; University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Högler+W%22">Högler W</searchLink>; Johannes Kepler University Linz, Linz, Austria.; University of Birmingham, Birmingham, UK.<br /><searchLink fieldCode="AU" term="%22Boot+AM%22">Boot AM</searchLink>; University Medical Center Groningen, University of Groningen, Groningen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Padidela+R%22">Padidela R</searchLink>; Royal Manchester Children's Hospital and Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22Van't+Hoff+W%22">Van't Hoff W</searchLink>; Great Ormond Street Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Gottesman+GS%22">Gottesman GS</searchLink>; Shriners Hospitals for Children - St. Louis, St Louis, MO, USA.<br /><searchLink fieldCode="AU" term="%22Chen+A%22">Chen A</searchLink>; Ultragenyx Pharmaceutical Inc., Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Skrinar+A%22">Skrinar A</searchLink>; Ultragenyx Pharmaceutical Inc., Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Scott+Roberts+M%22">Scott Roberts M</searchLink>; Ultragenyx Pharmaceutical Inc., Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Carpenter+TO%22">Carpenter TO</searchLink>; Yale University School of Medicine, New Haven, CT, USA.
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  Data: <searchLink fieldCode="JN" term="%220375362%22">The Journal of clinical endocrinology and metabolism</searchLink> [J Clin Endocrinol Metab] 2022 Feb 17; Vol. 107 (3), pp. 813-824.
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