View in EDS HTML Full Text PDF Full Text

BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.

Saved in:
Bibliographic Details
Title: BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
Authors: Gorombei P; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Guidez F; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Ganesan S; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Chiquet M; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Pellagatti A; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, and BRC Haematology Theme, Oxford OX3 9DU, UK., Goursaud L; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Tekin N; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Beurlet S; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Patel S; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Guerenne L; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Le Pogam C; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Setterblad N; Imagerie Département, Université de Paris, Institut de la Recherche Saint-Louis, 75010 Paris, France., de la Grange P; GenoSplice Technology, Paris Biotech Santé, 29 Rue du Faubourg Saint-Jacques, 75014 Paris, France., LeBoeuf C; INSERM UMR-S942, Université de Paris, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France., Janin A; INSERM UMR-S942, Université de Paris, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France., Noguera ME; Department of Cytology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France., Sarda-Mantel L; Radiopharmacie AP-HP, Hôpital Saint-Louis, Service Medicine Nuclear, AP-HP Lariboisiere, 75010 Paris, France., Merlet P; Nuclear Medicine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France., Boultwood J; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, and BRC Haematology Theme, Oxford OX3 9DU, UK., Konopleva M; M. D. Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA., Andreeff M; M. D. Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA., West R; Department of Public Health, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Pla M; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Adès L; INSERM UMR-S944, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France., Fenaux P; INSERM UMR-S944, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France., Krief P; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Chomienne C; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France., Omidvar N; Department of Haematology, Cardiff University School of Medicine, Cardiff CF14 4XN, UK., Padua RA; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.
Source: International journal of molecular sciences [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). Date of Electronic Publication: 2021 Sep 30.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 34638998
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Gorombei+P%22">Gorombei P</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Guidez+F%22">Guidez F</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Ganesan+S%22">Ganesan S</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Chiquet+M%22">Chiquet M</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Pellagatti+A%22">Pellagatti A</searchLink>; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, and BRC Haematology Theme, Oxford OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Goursaud+L%22">Goursaud L</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Tekin+N%22">Tekin N</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Beurlet+S%22">Beurlet S</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Patel+S%22">Patel S</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Guerenne+L%22">Guerenne L</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Le+Pogam+C%22">Le Pogam C</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Setterblad+N%22">Setterblad N</searchLink>; Imagerie Département, Université de Paris, Institut de la Recherche Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22de+la+Grange+P%22">de la Grange P</searchLink>; GenoSplice Technology, Paris Biotech Santé, 29 Rue du Faubourg Saint-Jacques, 75014 Paris, France.<br /><searchLink fieldCode="AU" term="%22LeBoeuf+C%22">LeBoeuf C</searchLink>; INSERM UMR-S942, Université de Paris, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Janin+A%22">Janin A</searchLink>; INSERM UMR-S942, Université de Paris, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Noguera+ME%22">Noguera ME</searchLink>; Department of Cytology, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Sarda-Mantel+L%22">Sarda-Mantel L</searchLink>; Radiopharmacie AP-HP, Hôpital Saint-Louis, Service Medicine Nuclear, AP-HP Lariboisiere, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Merlet+P%22">Merlet P</searchLink>; Nuclear Medicine, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Boultwood+J%22">Boultwood J</searchLink>; Blood Cancer UK Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, and BRC Haematology Theme, Oxford OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Konopleva+M%22">Konopleva M</searchLink>; M. D. Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22Andreeff+M%22">Andreeff M</searchLink>; M. D. Anderson Cancer Center, The University of Texas, Houston, TX 77030, USA.<br /><searchLink fieldCode="AU" term="%22West+R%22">West R</searchLink>; Department of Public Health, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Pla+M%22">Pla M</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Adès+L%22">Adès L</searchLink>; INSERM UMR-S944, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Fenaux+P%22">Fenaux P</searchLink>; INSERM UMR-S944, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Krief+P%22">Krief P</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Chomienne+C%22">Chomienne C</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.<br /><searchLink fieldCode="AU" term="%22Omidvar+N%22">Omidvar N</searchLink>; Department of Haematology, Cardiff University School of Medicine, Cardiff CF14 4XN, UK.<br /><searchLink fieldCode="AU" term="%22Padua+RA%22">Padua RA</searchLink>; INSERM UMR-S1131, Université de Paris, Institut de la Recherche Saint-Louis, Assistance Publique-Hôpitaux de Paris (AP-HP), Hôpital Saint-Louis Hôpital, 75010 Paris, France.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101092791%22">International journal of molecular sciences</searchLink> [Int J Mol Sci] 2021 Sep 30; Vol. 22 (19). <i>Date of Electronic Publication: </i>2021 Sep 30.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101092791 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1422-0067 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214220067%22">14220067 </searchLink><i>NLM ISO Abbreviation: </i>Int J Mol Sci <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34638998
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.3390/ijms221910658
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: BCL-2 Inhibitor ABT-737 Effectively Targets Leukemia-Initiating Cells with Differential Regulation of Relevant Genes Leading to Extended Survival in a NRAS/BCL-2 Mouse Model of High Risk-Myelodysplastic Syndrome.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Gorombei P
      – PersonEntity:
          Name:
            NameFull: Guidez F
      – PersonEntity:
          Name:
            NameFull: Ganesan S
      – PersonEntity:
          Name:
            NameFull: Chiquet M
      – PersonEntity:
          Name:
            NameFull: Pellagatti A
      – PersonEntity:
          Name:
            NameFull: Goursaud L
      – PersonEntity:
          Name:
            NameFull: Tekin N
      – PersonEntity:
          Name:
            NameFull: Beurlet S
      – PersonEntity:
          Name:
            NameFull: Patel S
      – PersonEntity:
          Name:
            NameFull: Guerenne L
      – PersonEntity:
          Name:
            NameFull: Le Pogam C
      – PersonEntity:
          Name:
            NameFull: Setterblad N
      – PersonEntity:
          Name:
            NameFull: de la Grange P
      – PersonEntity:
          Name:
            NameFull: LeBoeuf C
      – PersonEntity:
          Name:
            NameFull: Janin A
      – PersonEntity:
          Name:
            NameFull: Noguera ME
      – PersonEntity:
          Name:
            NameFull: Sarda-Mantel L
      – PersonEntity:
          Name:
            NameFull: Merlet P
      – PersonEntity:
          Name:
            NameFull: Boultwood J
      – PersonEntity:
          Name:
            NameFull: Konopleva M
      – PersonEntity:
          Name:
            NameFull: Andreeff M
      – PersonEntity:
          Name:
            NameFull: West R
      – PersonEntity:
          Name:
            NameFull: Pla M
      – PersonEntity:
          Name:
            NameFull: Adès L
      – PersonEntity:
          Name:
            NameFull: Fenaux P
      – PersonEntity:
          Name:
            NameFull: Krief P
      – PersonEntity:
          Name:
            NameFull: Chomienne C
      – PersonEntity:
          Name:
            NameFull: Omidvar N
      – PersonEntity:
          Name:
            NameFull: Padua RA
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 30
              M: 09
              Text: 2021 Sep 30
              Type: published
              Y: 2021
          Identifiers:
            – Type: issn-electronic
              Value: 1422-0067
          Numbering:
            – Type: volume
              Value: 22
            – Type: issue
              Value: 19
          Titles:
            – TitleFull: International journal of molecular sciences
              Type: main
ResultId 1