Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.

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Title: Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
Authors: Song B; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Chen Y; Laboratory of Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA., Liu X; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Yuan F; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Tan EYJ; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore., Lei Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Song N; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Han Y; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Pascal BD; Omics Informatics LLC, Honolulu, HI 96813, USA., Griffin PR; The Scripps Research Institute, Department of Molecular Medicine, Jupiter, FL 33458, USA., Luo C; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China., Wu B; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore., Luo D; Lee Kong Chian School of Medicine, Nanyang Technological University, EMB 03-07, 59 Nanyang Drive, Singapore 636921, Singapore; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore., Zheng J; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China. Electronic address: jzheng@simm.ac.cn.
Source: Immunity [Immunity] 2021 Oct 12; Vol. 54 (10), pp. 2218-2230.e5.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Ordered assembly of the cytosolic RNA-sensing MDA5-MAVS signaling complex via binding to unanchored K63-linked poly-ubiquitin chains.
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  Data: <searchLink fieldCode="AU" term="%22Song+B%22">Song B</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; Laboratory of Molecular Biology, NIDDK, National Institutes of Health, Bethesda, MD 20892, USA.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Yuan+F%22">Yuan F</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Tan+EYJ%22">Tan EYJ</searchLink>; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore.<br /><searchLink fieldCode="AU" term="%22Lei+Y%22">Lei Y</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Song+N%22">Song N</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Han+Y%22">Han Y</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Pascal+BD%22">Pascal BD</searchLink>; Omics Informatics LLC, Honolulu, HI 96813, USA.<br /><searchLink fieldCode="AU" term="%22Griffin+PR%22">Griffin PR</searchLink>; The Scripps Research Institute, Department of Molecular Medicine, Jupiter, FL 33458, USA.<br /><searchLink fieldCode="AU" term="%22Luo+C%22">Luo C</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China; The Center for Chemical Biology, Drug Discovery and Design Center, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China.<br /><searchLink fieldCode="AU" term="%22Wu+B%22">Wu B</searchLink>; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore.<br /><searchLink fieldCode="AU" term="%22Luo+D%22">Luo D</searchLink>; Lee Kong Chian School of Medicine, Nanyang Technological University, EMB 03-07, 59 Nanyang Drive, Singapore 636921, Singapore; NTU Institute of Structural Biology, Nanyang Technological University, EMB 06-01, 59 Nanyang Drive, Singapore 636921, Singapore; School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 636921, Singapore.<br /><searchLink fieldCode="AU" term="%22Zheng+J%22">Zheng J</searchLink>; Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, UCAS, Hangzhou 310024, China. Electronic address: jzheng@simm.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%229432918%22">Immunity</searchLink> [Immunity] 2021 Oct 12; Vol. 54 (10), pp. 2218-2230.e5.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9432918 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4180 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210747613%22">10747613 </searchLink><i>NLM ISO Abbreviation: </i>Immunity <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.immuni.2021.09.008
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              Text: 2021 Oct 12
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