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Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol.

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Title: Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol.
Authors: Gregory JW; Division of Population Medicine, Cardiff University, Cardiff, South Glamorgan, UK., Carter K; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK k.carter@swansea.ac.uk., Cheung WY; Diabetes Research Unit Cymru (DRUC), Swansea University, Swansea, West Glamorgan, UK., Holland G; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK., Bowen-Morris J; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK., Luzio S; Diabetes Research Unit Cymru (DRUC), Swansea University, Swansea, West Glamorgan, UK., Dunseath G; Diabetes Research Unit Cymru (DRUC), Swansea University, Swansea, West Glamorgan, UK., Tree T; Peter Gorer Department of Immunobiology, King's College London, London, UK.; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK., Yang JHM; Peter Gorer Department of Immunobiology, King's College London, London, UK.; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK., Marwaha A; Department of Molecular Genetics, Cumming School of Medicine, The University of Calgary, Calgary, Alberta, Canada., Ali MA; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK., Bashir N; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK., Hutchings HA; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK., Fegan GW; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK., Stenson R; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK., Hiles S; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK., Marques-Jones S; Patient and Public Representative, Ammanford, West Glamorgan, UK., Brown A; Patient and Public Representative, Cardiff, UK., Tatovic D; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK., Dayan C; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK.
Source: BMJ open [BMJ Open] 2021 Oct 18; Vol. 11 (10), pp. e049595. Date of Electronic Publication: 2021 Oct 18.
Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Phase II multicentre, double-blind, randomised trial of ustekinumab in adolescents with new-onset type 1 diabetes (USTEK1D): trial protocol.
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  Data: <searchLink fieldCode="AU" term="%22Gregory+JW%22">Gregory JW</searchLink>; Division of Population Medicine, Cardiff University, Cardiff, South Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Carter+K%22">Carter K</searchLink>; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK k.carter@swansea.ac.uk.<br /><searchLink fieldCode="AU" term="%22Cheung+WY%22">Cheung WY</searchLink>; Diabetes Research Unit Cymru (DRUC), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Holland+G%22">Holland G</searchLink>; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Bowen-Morris+J%22">Bowen-Morris J</searchLink>; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Luzio+S%22">Luzio S</searchLink>; Diabetes Research Unit Cymru (DRUC), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Dunseath+G%22">Dunseath G</searchLink>; Diabetes Research Unit Cymru (DRUC), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Tree+T%22">Tree T</searchLink>; Peter Gorer Department of Immunobiology, King's College London, London, UK.; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Yang+JHM%22">Yang JHM</searchLink>; Peter Gorer Department of Immunobiology, King's College London, London, UK.; National Institute for Health Research (NIHR) Biomedical Research Center (BRC), Guy's and St Thomas' NHS Foundation Trust and King's College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Marwaha+A%22">Marwaha A</searchLink>; Department of Molecular Genetics, Cumming School of Medicine, The University of Calgary, Calgary, Alberta, Canada.<br /><searchLink fieldCode="AU" term="%22Ali+MA%22">Ali MA</searchLink>; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Bashir+N%22">Bashir N</searchLink>; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Hutchings+HA%22">Hutchings HA</searchLink>; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Fegan+GW%22">Fegan GW</searchLink>; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Stenson+R%22">Stenson R</searchLink>; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Hiles+S%22">Hiles S</searchLink>; Swansea Trials Unit (STU), Swansea University, Swansea, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Marques-Jones+S%22">Marques-Jones S</searchLink>; Patient and Public Representative, Ammanford, West Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Brown+A%22">Brown A</searchLink>; Patient and Public Representative, Cardiff, UK.<br /><searchLink fieldCode="AU" term="%22Tatovic+D%22">Tatovic D</searchLink>; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK.<br /><searchLink fieldCode="AU" term="%22Dayan+C%22">Dayan C</searchLink>; Diabetes Research Group, Cardiff University, Cardiff, South Glamorgan, UK.
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  Data: <searchLink fieldCode="JN" term="%22101552874%22">BMJ open</searchLink> [BMJ Open] 2021 Oct 18; Vol. 11 (10), pp. e049595. <i>Date of Electronic Publication: </i>2021 Oct 18.
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  Data: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't
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