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Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.

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Title: Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
Authors: Ting HC; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan., Yang HI; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan., Harn HJ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Pathology, Hualien Tzu Chi Hospital and Tzu Chi University, Hualien 97002, Taiwan., Chiu IM; Institute of Cellular and System Medicine, National Health Research Institutes, Miaoli 35053, Taiwan., Su HL; Department of Life Sciences, National Chung Hsing University, Taichung 40227, Taiwan., Li X; Waisman Center, University of Wisconsin, Madison, WI 53705, USA., Chen MF; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan., Ho TJ; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien 97004, Taiwan., Liu CA; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Neuroscience Center, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan., Tsai YJ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan., Chiou TW; Department of Life Science, National Dong Hwa University, Hualien 97441, Taiwan., Lin SZ; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan., Chang CY; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Neuroscience Center, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.
Source: Cells [Cells] 2021 Oct 16; Vol. 10 (10). Date of Electronic Publication: 2021 Oct 16.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Coactivation of GSK3β and IGF-1 Attenuates Amyotrophic Lateral Sclerosis Nerve Fiber Cytopathies in SOD1 Mutant Patient-Derived Motor Neurons.
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  Data: <searchLink fieldCode="AU" term="%22Ting+HC%22">Ting HC</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yang+HI%22">Yang HI</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.<br /><searchLink fieldCode="AU" term="%22Harn+HJ%22">Harn HJ</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Pathology, Hualien Tzu Chi Hospital and Tzu Chi University, Hualien 97002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+IM%22">Chiu IM</searchLink>; Institute of Cellular and System Medicine, National Health Research Institutes, Miaoli 35053, Taiwan.<br /><searchLink fieldCode="AU" term="%22Su+HL%22">Su HL</searchLink>; Department of Life Sciences, National Chung Hsing University, Taichung 40227, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Waisman Center, University of Wisconsin, Madison, WI 53705, USA.<br /><searchLink fieldCode="AU" term="%22Chen+MF%22">Chen MF</searchLink>; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Ho+TJ%22">Ho TJ</searchLink>; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.; Department of Chinese Medicine, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Integration Center of Traditional Chinese and Modern Medicine, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; School of Post-Baccalaureate Chinese Medicine, Tzu Chi University, Hualien 97004, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+CA%22">Liu CA</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Neuroscience Center, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Tsai+YJ%22">Tsai YJ</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiou+TW%22">Chiou TW</searchLink>; Department of Life Science, National Dong Hwa University, Hualien 97441, Taiwan.<br /><searchLink fieldCode="AU" term="%22Lin+SZ%22">Lin SZ</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Institute of Medical Sciences, Tzu Chi University, Hualien 97004, Taiwan.; Department of Neurosurgery, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chang+CY%22">Chang CY</searchLink>; Bioinnovation Center, Buddhist Tzu Chi Medical Foundation, Hualien 97002, Taiwan.; Department of Medical Research, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.; Neuroscience Center, Hualien Tzu Chi Hospital, Hualien 97002, Taiwan.
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  Data: <searchLink fieldCode="JN" term="%22101600052%22">Cells</searchLink> [Cells] 2021 Oct 16; Vol. 10 (10). <i>Date of Electronic Publication: </i>2021 Oct 16.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101600052 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2073-4409 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220734409%22">20734409 </searchLink><i>NLM ISO Abbreviation: </i>Cells <i>Subsets: </i>MEDLINE
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