Lower cerebral oxygen utilization is associated with Alzheimer's disease-related neurodegeneration and poorer cognitive performance among apolipoprotein E ε4 carriers.

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Title: Lower cerebral oxygen utilization is associated with Alzheimer's disease-related neurodegeneration and poorer cognitive performance among apolipoprotein E ε4 carriers.
Authors: Robb WH; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Khan OA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biostatistics, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA., Ahmed HA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Li J; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Moore EE; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Cambronero FE; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Pechman KR; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA., Liu D; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biostatistics, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA., Gifford KA; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Neurology, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA., Landman BA; Department of Neurology, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Biomedical Engineering, 5718Vanderbilt University, Vanderbilt University, Nashville, TN, USA.; Department of Electrical Engineering and Computer Science, 5718Vanderbilt University, Vanderbilt University, Nashville, TN, USA.; Department of Radiology and Radiological Sciences, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA., Donahue MJ; Department of Neurology, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Radiology and Radiological Sciences, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, Nashville, TN, USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Neurology, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA., Jefferson AL; Vanderbilt Memory and Alzheimer's Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Neurology, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA.; Department of Medicine, 12328Vanderbilt University Medical Center, Vanderbilt University Medical Center, Nashville, TN, USA.
Source: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2022 Apr; Vol. 42 (4), pp. 642-655. Date of Electronic Publication: 2021 Nov 07.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: SAGE Publications Country of Publication: United States NLM ID: 8112566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-7016 (Electronic) Linking ISSN: 0271678X NLM ISO Abbreviation: J Cereb Blood Flow Metab Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1559-7016
DOI:10.1177/0271678X211056393