Diverse alterations associated with resistance to KRAS(G12C) inhibition.
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| Title: | Diverse alterations associated with resistance to KRAS(G12C) inhibition. |
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| Authors: | Zhao Y; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA., Murciano-Goroff YR; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Xue JY; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA., Ang A; Amgen, Thousand Oaks, CA, USA., Lucas J; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA., Mai TT; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA., Da Cruz Paula AF; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Saiki AY; Amgen, Thousand Oaks, CA, USA., Mohn D; Amgen, Thousand Oaks, CA, USA., Achanta P; Amgen, Thousand Oaks, CA, USA., Sisk AE; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Arora KS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Roy RS; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA., Kim D; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA., Li C; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA., Lim LP; Resolution Bioscience, Kirkland, WA, USA., Li M; Resolution Bioscience, Kirkland, WA, USA., Bahr A; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Loomis BR; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., de Stanchina E; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Reis-Filho JS; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Weigelt B; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Berger M; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Riely G; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Arbour KC; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lipford JR; Amgen, Thousand Oaks, CA, USA., Li BT; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lito P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA. litop@mskcc.org.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. litop@mskcc.org.; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA. litop@mskcc.org.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. litop@mskcc.org. |
| Source: | Nature [Nature] 2021 Nov; Vol. 599 (7886), pp. 679-683. Date of Electronic Publication: 2021 Nov 10. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34759319 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Diverse alterations associated with resistance to KRAS(G12C) inhibition. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhao+Y%22">Zhao Y</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Murciano-Goroff+YR%22">Murciano-Goroff YR</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Xue+JY%22">Xue JY</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Ang+A%22">Ang A</searchLink>; Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Lucas+J%22">Lucas J</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Mai+TT%22">Mai TT</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Da+Cruz+Paula+AF%22">Da Cruz Paula AF</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Saiki+AY%22">Saiki AY</searchLink>; Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Mohn+D%22">Mohn D</searchLink>; Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Achanta+P%22">Achanta P</searchLink>; Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Sisk+AE%22">Sisk AE</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Arora+KS%22">Arora KS</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Roy+RS%22">Roy RS</searchLink>; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Kim+D%22">Kim D</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lim+LP%22">Lim LP</searchLink>; Resolution Bioscience, Kirkland, WA, USA.<br /><searchLink fieldCode="AU" term="%22Li+M%22">Li M</searchLink>; Resolution Bioscience, Kirkland, WA, USA.<br /><searchLink fieldCode="AU" term="%22Bahr+A%22">Bahr A</searchLink>; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Loomis+BR%22">Loomis BR</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22de+Stanchina+E%22">de Stanchina E</searchLink>; Antitumor Assessment Core Facility, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Reis-Filho+JS%22">Reis-Filho JS</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Weigelt+B%22">Weigelt B</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Berger+M%22">Berger M</searchLink>; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Center for Molecular Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Riely+G%22">Riely G</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Arbour+KC%22">Arbour KC</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lipford+JR%22">Lipford JR</searchLink>; Amgen, Thousand Oaks, CA, USA.<br /><searchLink fieldCode="AU" term="%22Li+BT%22">Li BT</searchLink>; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Lito+P%22">Lito P</searchLink>; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer, New York, NY, USA. litop@mskcc.org.; Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA. litop@mskcc.org.; Weill Cornell-Rockefeller-Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY, USA. litop@mskcc.org.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. litop@mskcc.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2021 Nov; Vol. 599 (7886), pp. 679-683. <i>Date of Electronic Publication: </i>2021 Nov 10. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>0410462 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1476-4687 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200280836%22">00280836 </searchLink><i>NLM ISO Abbreviation: </i>Nature <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34759319 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41586-021-04065-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 679 Titles: – TitleFull: Diverse alterations associated with resistance to KRAS(G12C) inhibition. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhao Y – PersonEntity: Name: NameFull: Murciano-Goroff YR – PersonEntity: Name: NameFull: Xue JY – PersonEntity: Name: NameFull: Ang A – PersonEntity: Name: NameFull: Lucas J – PersonEntity: Name: NameFull: Mai TT – PersonEntity: Name: NameFull: Da Cruz Paula AF – PersonEntity: Name: NameFull: Saiki AY – PersonEntity: Name: NameFull: Mohn D – PersonEntity: Name: NameFull: Achanta P – PersonEntity: Name: NameFull: Sisk AE – PersonEntity: Name: NameFull: Arora KS – PersonEntity: Name: NameFull: Roy RS – PersonEntity: Name: NameFull: Kim D – PersonEntity: Name: NameFull: Li C – PersonEntity: Name: NameFull: Lim LP – PersonEntity: Name: NameFull: Li M – PersonEntity: Name: NameFull: Bahr A – PersonEntity: Name: NameFull: Loomis BR – PersonEntity: Name: NameFull: de Stanchina E – PersonEntity: Name: NameFull: Reis-Filho JS – PersonEntity: Name: NameFull: Weigelt B – PersonEntity: Name: NameFull: Berger M – PersonEntity: Name: NameFull: Riely G – PersonEntity: Name: NameFull: Arbour KC – PersonEntity: Name: NameFull: Lipford JR – PersonEntity: Name: NameFull: Li BT – PersonEntity: Name: NameFull: Lito P IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: 2021 Nov Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1476-4687 Numbering: – Type: volume Value: 599 – Type: issue Value: 7886 Titles: – TitleFull: Nature Type: main |
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