Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell-derived cardiomyocytes.

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Title: Conventional rigid 2D substrates cause complex contractile signals in monolayers of human induced pluripotent stem cell-derived cardiomyocytes.
Authors: Huethorst E; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.; Division of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Glasgow, UK., Mortensen P; School of Mathematics and Statistics, University of Glasgow, Glasgow, UK., Simitev RD; School of Mathematics and Statistics, University of Glasgow, Glasgow, UK., Gao H; School of Mathematics and Statistics, University of Glasgow, Glasgow, UK., Pohjolainen L; Drug Research Program and Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Talman V; Drug Research Program and Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Ruskoaho H; Drug Research Program and Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland., Burton FL; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK., Gadegaard N; Division of Biomedical Engineering, James Watt School of Engineering, University of Glasgow, Glasgow, UK., Smith GL; Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Source: The Journal of physiology [J Physiol] 2022 Feb; Vol. 600 (3), pp. 483-507. Date of Electronic Publication: 2021 Dec 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cambridge Univ. Press Country of Publication: England NLM ID: 0266262 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-7793 (Electronic) Linking ISSN: 00223751 NLM ISO Abbreviation: J Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-7793
DOI:10.1113/JP282228