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Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.

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Title: Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
Authors: Erener S; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg, Germany., Ellis CE; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Ramzy A; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Glavas MM; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., O'Dwyer S; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Pereira S; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Wang T; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Pang J; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Bruin JE; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; Department of Biology and Institute of Biochemistry, Carleton University, Ottawa, ON, Canada., Riedel MJ; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Baker RK; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Webber TD; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Lesina M; Comprehensive Cancer Center Munich, Technical University of Munich, Munich, Germany., Blüher M; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany., Algül H; Comprehensive Cancer Center Munich, Technical University of Munich, Munich, Germany., Kopp JL; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada., Herzig S; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg, Germany.; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany.; Technical University Munich, 85764 Neuherberg, Germany.; Deutsches Zentrum für Diabetesforschung, 85764 Neuherberg, Germany., Kieffer TJ; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC, Canada.; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.
Source: Cell reports. Medicine [Cell Rep Med] 2021 Nov 11; Vol. 2 (11), pp. 100434. Date of Electronic Publication: 2021 Nov 11 (Print Publication: 2021).
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med
Database: MEDLINE Ultimate
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  Data: Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice.
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  Data: <searchLink fieldCode="AU" term="%22Erener+S%22">Erener S</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Ellis+CE%22">Ellis CE</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Ramzy+A%22">Ramzy A</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Glavas+MM%22">Glavas MM</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22O'Dwyer+S%22">O'Dwyer S</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Pereira+S%22">Pereira S</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+T%22">Wang T</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Pang+J%22">Pang J</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Bruin+JE%22">Bruin JE</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; Department of Biology and Institute of Biochemistry, Carleton University, Ottawa, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Riedel+MJ%22">Riedel MJ</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Baker+RK%22">Baker RK</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Webber+TD%22">Webber TD</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Lesina+M%22">Lesina M</searchLink>; Comprehensive Cancer Center Munich, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Blüher+M%22">Blüher M</searchLink>; Helmholtz Institute for Metabolic, Obesity and Vascular Research (HI-MAG) of the Helmholtz Zentrum München at the University of Leipzig and University Hospital Leipzig, Leipzig, Germany.; Medical Department III - Endocrinology, Nephrology, Rheumatology, University of Leipzig Medical Center, Leipzig, Germany.<br /><searchLink fieldCode="AU" term="%22Algül+H%22">Algül H</searchLink>; Comprehensive Cancer Center Munich, Technical University of Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Kopp+JL%22">Kopp JL</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Herzig+S%22">Herzig S</searchLink>; Institute for Diabetes and Cancer, Helmholtz Center Munich, Neuherberg, Germany.; Joint Heidelberg-IDC Translational Diabetes Program, Inner Medicine 1, Heidelberg University Hospital, Heidelberg, Germany.; Technical University Munich, 85764 Neuherberg, Germany.; Deutsches Zentrum für Diabetesforschung, 85764 Neuherberg, Germany.<br /><searchLink fieldCode="AU" term="%22Kieffer+TJ%22">Kieffer TJ</searchLink>; Department of Cellular & Physiological Sciences, Life Sciences Institute, University of British Columbia, Vancouver, BC, Canada.; Department of Surgery, University of British Columbia, Vancouver, BC, Canada.; School of Biomedical Engineering, University of British Columbia, Vancouver, BC, Canada.
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  Data: <searchLink fieldCode="JN" term="%22101766894%22">Cell reports. Medicine</searchLink> [Cell Rep Med] 2021 Nov 11; Vol. 2 (11), pp. 100434. <i>Date of Electronic Publication: </i>2021 Nov 11 (<i>Print Publication: </i>2021).
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