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Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.

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Title: Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.
Authors: Liebmann M; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Korn L; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Janoschka C; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Albrecht S; Institute of Neuropathology, University Hospital Münster, Münster 48149, Germany., Lauks S; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Herrmann AM; Department of Neurology, University Hospital Düsseldorf, Düsseldorf 40225, Germany., Schulte-Mecklenbeck A; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Schwab N; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Schneider-Hohendorf T; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Eveslage M; Institute of Biostatistics and Clinical Research, University of Münster, Münster 48149, Germany., Wildemann B; Molecular Neuroimmunology Group, Department of Neurology, University of Heidelberg, Heidelberg 69120, Germany., Luessi F; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany., Schmidt S; Bonn Neurological Practice, Bonn 53111, Germany., Diebold M; Laboratory of Clinical Neuroimmunology, Neurologic Clinic and Policlinic, Departments of Biomedicine and Clinical Research, University Hospital Basel, and University of Basel, Basel 4031, Switzerland., Bittner S; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany., Gross CC; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Kovac S; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Zipp F; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany., Derfuss T; Laboratory of Clinical Neuroimmunology, Neurologic Clinic and Policlinic, Departments of Biomedicine and Clinical Research, University Hospital Basel, and University of Basel, Basel 4031, Switzerland., Kuhlmann T; Institute of Neuropathology, University Hospital Münster, Münster 48149, Germany., König S; Core Unit Proteomics, Interdisciplinary Clinical Research Center, University of Münster, Münster 48149, Germany., Meuth SG; Department of Neurology, University Hospital Düsseldorf, Düsseldorf 40225, Germany., Wiendl H; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany., Klotz L; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.
Source: Brain : a journal of neurology [Brain] 2021 Nov 29; Vol. 144 (10), pp. 3126-3141.
Publication Type: Clinical Trial, Phase IV; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 0372537 Publication Model: Print Cited Medium: Internet ISSN: 1460-2156 (Electronic) Linking ISSN: 00068950 NLM ISO Abbreviation: Brain Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity.
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  Data: <searchLink fieldCode="AU" term="%22Liebmann+M%22">Liebmann M</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Korn+L%22">Korn L</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Janoschka+C%22">Janoschka C</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Albrecht+S%22">Albrecht S</searchLink>; Institute of Neuropathology, University Hospital Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Lauks+S%22">Lauks S</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Herrmann+AM%22">Herrmann AM</searchLink>; Department of Neurology, University Hospital Düsseldorf, Düsseldorf 40225, Germany.<br /><searchLink fieldCode="AU" term="%22Schulte-Mecklenbeck+A%22">Schulte-Mecklenbeck A</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Schwab+N%22">Schwab N</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Schneider-Hohendorf+T%22">Schneider-Hohendorf T</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Eveslage+M%22">Eveslage M</searchLink>; Institute of Biostatistics and Clinical Research, University of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Wildemann+B%22">Wildemann B</searchLink>; Molecular Neuroimmunology Group, Department of Neurology, University of Heidelberg, Heidelberg 69120, Germany.<br /><searchLink fieldCode="AU" term="%22Luessi+F%22">Luessi F</searchLink>; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany.<br /><searchLink fieldCode="AU" term="%22Schmidt+S%22">Schmidt S</searchLink>; Bonn Neurological Practice, Bonn 53111, Germany.<br /><searchLink fieldCode="AU" term="%22Diebold+M%22">Diebold M</searchLink>; Laboratory of Clinical Neuroimmunology, Neurologic Clinic and Policlinic, Departments of Biomedicine and Clinical Research, University Hospital Basel, and University of Basel, Basel 4031, Switzerland.<br /><searchLink fieldCode="AU" term="%22Bittner+S%22">Bittner S</searchLink>; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany.<br /><searchLink fieldCode="AU" term="%22Gross+CC%22">Gross CC</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Kovac+S%22">Kovac S</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Zipp+F%22">Zipp F</searchLink>; Department of Neurology, Focus Program Translational Neuroscience (FTN) and Immunotherapy (FZI), Rhine Main Neuroscience Network (rmn2), University Medical Center of the Johannes Gutenberg University Mainz, Mainz 55131, Germany.<br /><searchLink fieldCode="AU" term="%22Derfuss+T%22">Derfuss T</searchLink>; Laboratory of Clinical Neuroimmunology, Neurologic Clinic and Policlinic, Departments of Biomedicine and Clinical Research, University Hospital Basel, and University of Basel, Basel 4031, Switzerland.<br /><searchLink fieldCode="AU" term="%22Kuhlmann+T%22">Kuhlmann T</searchLink>; Institute of Neuropathology, University Hospital Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22König+S%22">König S</searchLink>; Core Unit Proteomics, Interdisciplinary Clinical Research Center, University of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Meuth+SG%22">Meuth SG</searchLink>; Department of Neurology, University Hospital Düsseldorf, Düsseldorf 40225, Germany.<br /><searchLink fieldCode="AU" term="%22Wiendl+H%22">Wiendl H</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.<br /><searchLink fieldCode="AU" term="%22Klotz+L%22">Klotz L</searchLink>; Department of Neurology with Institute of Translational Neurology, University Hospital of Münster, Münster 48149, Germany.
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