Response to comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics".
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| Title: | Response to comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics". |
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| Authors: | Bovijn J; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Krebs K; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Chen CY; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Boxall R; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Censin JC; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Ferreira T; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK., Pulit SL; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.; Department of Genetics, University Medical Center Utrecht, 3584 CX Utrecht, Netherlands., Glastonbury CA; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK., Laber S; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Millwood IY; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Lin K; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Li L; Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing 100191, China., Chen Z; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Milani L; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Smith GD; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK., Walters RG; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK., Mägi R; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia., Neale BM; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA., Lindgren CM; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK., Holmes MV; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK. |
| Source: | Science translational medicine [Sci Transl Med] 2021 Dec; Vol. 13 (622), pp. eabf4530. Date of Electronic Publication: 2021 Dec 01. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 34851696 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Response to comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics". – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Bovijn+J%22">Bovijn J</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.<br /><searchLink fieldCode="AU" term="%22Krebs+K%22">Krebs K</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.<br /><searchLink fieldCode="AU" term="%22Chen+CY%22">Chen CY</searchLink>; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Boxall+R%22">Boxall R</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Censin+JC%22">Censin JC</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.<br /><searchLink fieldCode="AU" term="%22Ferreira+T%22">Ferreira T</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.<br /><searchLink fieldCode="AU" term="%22Pulit+SL%22">Pulit SL</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.; Department of Genetics, University Medical Center Utrecht, 3584 CX Utrecht, Netherlands.<br /><searchLink fieldCode="AU" term="%22Glastonbury+CA%22">Glastonbury CA</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.<br /><searchLink fieldCode="AU" term="%22Laber+S%22">Laber S</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.<br /><searchLink fieldCode="AU" term="%22Millwood+IY%22">Millwood IY</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Lin+K%22">Lin K</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; Department of Epidemiology and Biostatistics, Peking University Health Science Centre, Peking University, Beijing 100191, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Milani+L%22">Milani L</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.<br /><searchLink fieldCode="AU" term="%22Smith+GD%22">Smith GD</searchLink>; Medical Research Council Integrative Epidemiology Unit, University of Bristol, Bristol BS8 2BN, UK.; Population Health Sciences, Bristol Medical School, University of Bristol, Barley House, Oakfield Grove, Bristol BS8 2BN, UK.<br /><searchLink fieldCode="AU" term="%22Walters+RG%22">Walters RG</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.<br /><searchLink fieldCode="AU" term="%22Mägi+R%22">Mägi R</searchLink>; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu 51010, Estonia.<br /><searchLink fieldCode="AU" term="%22Neale+BM%22">Neale BM</searchLink>; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA 02114, USA.; Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA.<br /><searchLink fieldCode="AU" term="%22Lindgren+CM%22">Lindgren CM</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Wellcome Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Program in Medical and Population Genetics, Broad Institute, Cambridge, MA 02142, USA.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Holmes+MV%22">Holmes MV</searchLink>; Big Data Institute at the Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford OX3 7FZ, UK.; Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; Medical Research Council Population Health Research Unit (MRC PHRU), Nuffield Department of Population Health, University of Oxford, Oxford OX3 7LF, UK.; National Institute for Health Research Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, John Radcliffe Hospital, Oxford OX3 9DU, UK. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2021 Dec; Vol. 13 (622), pp. eabf4530. <i>Date of Electronic Publication: </i>2021 Dec 01. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Comment – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101505086 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1946-6242 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219466234%22">19466234 </searchLink><i>NLM ISO Abbreviation: </i>Sci Transl Med <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=34851696 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1126/scitranslmed.abf4530 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: eabf4530 Titles: – TitleFull: Response to comment on "Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics". Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Bovijn J – PersonEntity: Name: NameFull: Krebs K – PersonEntity: Name: NameFull: Chen CY – PersonEntity: Name: NameFull: Boxall R – PersonEntity: Name: NameFull: Censin JC – PersonEntity: Name: NameFull: Ferreira T – PersonEntity: Name: NameFull: Pulit SL – PersonEntity: Name: NameFull: Glastonbury CA – PersonEntity: Name: NameFull: Laber S – PersonEntity: Name: NameFull: Millwood IY – PersonEntity: Name: NameFull: Lin K – PersonEntity: Name: NameFull: Li L – PersonEntity: Name: NameFull: Chen Z – PersonEntity: Name: NameFull: Milani L – PersonEntity: Name: NameFull: Smith GD – PersonEntity: Name: NameFull: Walters RG – PersonEntity: Name: NameFull: Mägi R – PersonEntity: Name: NameFull: Neale BM – PersonEntity: Name: NameFull: Lindgren CM – PersonEntity: Name: NameFull: Holmes MV IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: 2021 Dec Type: published Y: 2021 Identifiers: – Type: issn-electronic Value: 1946-6242 Numbering: – Type: volume Value: 13 – Type: issue Value: 622 Titles: – TitleFull: Science translational medicine Type: main |
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