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Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7.

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Title: Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7.
Authors: Switonski PM; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Str., 61-704 Poznan, Poland., Delaney JR; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA., Bartelt LC; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA., Niu C; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA., Ramos-Zapatero M; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA., Spann NJ; Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Alaghatta A; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA., Chen T; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA., Griffin EN; Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA., Bapat J; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA., Sopher BL; Department of Neurology, University of Washington Medical Center, Seattle, WA 98195, USA., La Spada AR; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; UCI Institute for Neurotherapeutics, University of California, Irvine, Irvine, CA 92697, USA. Electronic address: alaspada@uci.edu.
Source: Cell reports [Cell Rep] 2021 Nov 30; Vol. 37 (9), pp. 110062.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE
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  Data: Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7.
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  Data: <searchLink fieldCode="AU" term="%22Switonski+PM%22">Switonski PM</searchLink>; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medical Biotechnology, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Noskowskiego 12/14 Str., 61-704 Poznan, Poland.<br /><searchLink fieldCode="AU" term="%22Delaney+JR%22">Delaney JR</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Bartelt+LC%22">Bartelt LC</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Niu+C%22">Niu C</searchLink>; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA.<br /><searchLink fieldCode="AU" term="%22Ramos-Zapatero+M%22">Ramos-Zapatero M</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Spann+NJ%22">Spann NJ</searchLink>; Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Alaghatta+A%22">Alaghatta A</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Chen+T%22">Chen T</searchLink>; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Griffin+EN%22">Griffin EN</searchLink>; Department of Cellular & Molecular Medicine, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Bapat+J%22">Bapat J</searchLink>; Department of Pediatrics, University of California, San Diego, La Jolla, CA 92093, USA.<br /><searchLink fieldCode="AU" term="%22Sopher+BL%22">Sopher BL</searchLink>; Department of Neurology, University of Washington Medical Center, Seattle, WA 98195, USA.<br /><searchLink fieldCode="AU" term="%22La+Spada+AR%22">La Spada AR</searchLink>; Departments of Pathology & Laboratory Medicine, Neurology, and Biological Chemistry, University of California, Irvine, Irvine, CA 92697, USA; Department of Neurology, Duke University School of Medicine, Durham, NC 27710, USA; UCI Institute for Neurotherapeutics, University of California, Irvine, Irvine, CA 92697, USA. Electronic address: alaspada@uci.edu.
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