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Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death.

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Title: Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death.
Authors: Garciaz S; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, Marseille, France., Guirguis AA; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Müller S; Institut Curie, PSL Research University, CNRS UMR3666, INSERM U1143, Chemical Biology of Cancer, Paris, France., Brown FC; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia., Chan YC; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Motazedian A; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Rowe CL; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia., Kuzich JA; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Chan KL; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Tran K; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Smith L; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., MacPherson L; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Liddicoat B; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Lam EYN; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Cañeque T; Institut Curie, PSL Research University, CNRS UMR3666, INSERM U1143, Chemical Biology of Cancer, Paris, France., Burr ML; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia., Litalien V; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia., Pomilio G; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia., Poplineau M; Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, Marseille, France., Duprez E; Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, Marseille, France., Dawson SJ; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Centre for Cancer Research, University of Melbourne, Melbourne, Victoria, Australia., Ramm G; Monash Ramaciotti Centre for Cryo Electron Microscopy, Monash University, Melbourne, Victoria, Australia., Cox AG; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Victoria, Australia., Brown KK; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Victoria, Australia., Huang DCS; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia., Wei AH; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia., McArthur K; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia., Rodriguez R; Institut Curie, PSL Research University, CNRS UMR3666, INSERM U1143, Chemical Biology of Cancer, Paris, France., Dawson MA; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Centre for Cancer Research, University of Melbourne, Melbourne, Victoria, Australia.
Source: Cancer discovery [Cancer Discov] 2022 Mar 01; Vol. 12 (3), pp. 774-791.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Garciaz+S%22">Garciaz S</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Guirguis+AA%22">Guirguis AA</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Müller+S%22">Müller S</searchLink>; Institut Curie, PSL Research University, CNRS UMR3666, INSERM U1143, Chemical Biology of Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Brown+FC%22">Brown FC</searchLink>; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+YC%22">Chan YC</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Motazedian+A%22">Motazedian A</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Rowe+CL%22">Rowe CL</searchLink>; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Kuzich+JA%22">Kuzich JA</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Chan+KL%22">Chan KL</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Tran+K%22">Tran K</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Smith+L%22">Smith L</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22MacPherson+L%22">MacPherson L</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Liddicoat+B%22">Liddicoat B</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Lam+EYN%22">Lam EYN</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Cañeque+T%22">Cañeque T</searchLink>; Institut Curie, PSL Research University, CNRS UMR3666, INSERM U1143, Chemical Biology of Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Burr+ML%22">Burr ML</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.<br /><searchLink fieldCode="AU" term="%22Litalien+V%22">Litalien V</searchLink>; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Pomilio+G%22">Pomilio G</searchLink>; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Poplineau+M%22">Poplineau M</searchLink>; Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Duprez+E%22">Duprez E</searchLink>; Aix-Marseille University, INSERM U1068, CNRS, Institut Paoli-Calmettes, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Dawson+SJ%22">Dawson SJ</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Centre for Cancer Research, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Ramm+G%22">Ramm G</searchLink>; Monash Ramaciotti Centre for Cryo Electron Microscopy, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Cox+AG%22">Cox AG</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Brown+KK%22">Brown KK</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Department of Biochemistry and Pharmacology, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Huang+DCS%22">Huang DCS</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Wei+AH%22">Wei AH</searchLink>; Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22McArthur+K%22">McArthur K</searchLink>; Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Rodriguez+R%22">Rodriguez R</searchLink>; Institut Curie, PSL Research University, CNRS UMR3666, INSERM U1143, Chemical Biology of Cancer, Paris, France.<br /><searchLink fieldCode="AU" term="%22Dawson+MA%22">Dawson MA</searchLink>; Peter MacCallum Cancer Centre and Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Australia.; Centre for Cancer Research, University of Melbourne, Melbourne, Victoria, Australia.
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