Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective.
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| Title: | Current Practices, Gap Analysis, and Proposed Workflows for PBPK Modeling of Cytochrome P450 Induction: An Industry Perspective. |
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| Authors: | Hariparsad N; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Boston, Massachusetts, USA., Ramsden D; Takeda Development Center Americas, Inc., Cambridge, Massachusetts, USA., Taskar K; Drug Metabolism and Pharmacokinetics, IVIVT, GlaxoSmithKline, Stevenage, UK., Badée J; PK Sciences, Novartis Institutes for Biomedical Research, Basel, Switzerland., Venkatakrishnan K; EMD Serono Research & Development Institute, Inc, Billerica, Massachusetts, USA.; Merck KGaA, Darmstadt, Germany., Reddy MB; Department of Clinical Pharmacology, Oncology, Pfizer, Boulder, Colorado, USA., Cabalu T; Merck & Co., Inc., Kenilworth, New Jersey, USA., Mukherjee D; Clinical Pharmacology & Pharmacometrics, AbbVie, Inc., North Chicago, Illinois, USA., Rehmel J; Lilly Research Laboratories, Eli Lilly and Company, Indianapolis, Indiana, USA., Bolleddula J; EMD Serono Research & Development Institute, Inc, Billerica, Massachusetts, USA.; Merck KGaA, Darmstadt, Germany., Emami Riedmaier A; Bristol Meyers Squibb, Princeton, New Jersey, USA., Prakash C; Agios Pharmaceuticals, Cambridge, Massachusetts, USA., Chanteux H; UCB Biopharma, QP-DMPK, Brussels, Belgium., Mao J; Department of Drug Metabolism and Pharmacokinetics, Genentech, A Member of the Roche Group, South San Francisco, California, USA., Umehara K; Pharmaceutical Sciences, Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland., Shah K; Drug Metabolism and Pharmacokinetics, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts, USA., De Zwart L; DMPK, Janssen Research and Development, Beerse, Belgium., Dowty M; Department of Pharmacokinetics, Dynamic, and Metabolism, Pfizer, Cambridge, Massachusetts, USA., Kotsuma M; Quantitative Clinical Pharmacology, Daiichi-Sankyo, Inc., New Jersey, USA., Li M; Pharmacokinetics, Dynamics and Metabolism, Sanofi, Bridgewater, New Jersey, USA., Pilla Reddy V; Clinical Pharmacology and Pharmacometrics, Biopharmaceuticals R&D, AstraZeneca, Cambridge, UK., McGinnity DF; DMPK, Research and Early Development, Oncology R&D, AstraZeneca, Cambridge, UK., Parrott N; Pharmaceutical Sciences, Roche Pharma Research & Early Development, Roche Innovation Center Basel, Basel, Switzerland. |
| Source: | Clinical pharmacology and therapeutics [Clin Pharmacol Ther] 2022 Oct; Vol. 112 (4), pp. 770-781. Date of Electronic Publication: 2021 Dec 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 0372741 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-6535 (Electronic) Linking ISSN: 00099236 NLM ISO Abbreviation: Clin Pharmacol Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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