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The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals.

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Title: The protective gene dose effect of the APOE ε2 allele on gray matter volume in cognitively unimpaired individuals.
Authors: Salvadó G; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Ferreira D; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Department of Radiology, Mayo Clinic, Rochester, Minnesota, USA., Operto G; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Cumplido-Mayoral I; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain., Arenaza-Urquijo EM; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Cacciaglia R; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Falcon C; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain., Vilor-Tejedor N; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; Centre for Genomic Regulation (CRG), The Barcelona Institute for Science and Technology, Barcelona, Spain.; Department of Clinical Genetics, ERASMUS MC, Rotterdam, the Netherlands., Minguillon C; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; CIBER Fragilidad y Envejecimiento Saludable (CIBERFES), Madrid, Spain., Groot C; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., van der Flier WM; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; Department of Epidemiology & Biostatistics, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., Barkhof F; Department of Radiology and Nuclear Medicine, VU Medical Center, Neuroscience Campus Amsterdam, Amsterdam, the Netherlands.; Institutes of Neurology & Healthcare Engineering, University College London, London, UK., Scheltens P; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands., Ossenkoppele R; Alzheimer Center Amsterdam, Department of Neurology, Amsterdam Neuroscience, Vrije Universiteit Amsterdam, Amsterdam UMC, Amsterdam, the Netherlands.; Clinical Memory Research Unit, Lund University, Lund, Sweden., Kern S; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg, Gothenburg, Sweden., Zettergren A; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg, Gothenburg, Sweden., Skoog I; Neuropsychiatric Epidemiology Unit, Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, Centre for Ageing and Health (AgeCap) at the University of Gothenburg, Gothenburg, Sweden., Hort J; International Clinical Research Centre, St. Anne's University Hospital Brno, Brno, Czech Republic.; Memory Clinic, Department of Neurology, Charles University, 2nd Faculty of Medicine and Motol University Hospital, Prague, Czech Republic., Stomrud E; Department of Clinical Sciences, Clinical Memory Research Unit, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., van Westen D; Diagnostic Radiology, Institution for Clinical Sciences, Lund University, Lund, Sweden.; Image and Function, Skåne University Hospital, Lund, Sweden., Hansson O; Department of Clinical Sciences, Clinical Memory Research Unit, Lund University, Lund, Sweden.; Memory Clinic, Skåne University Hospital, Malmö, Sweden., Molinuevo JL; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain., Wahlund LO; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden., Westman E; Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Stockholm, Sweden.; Department of Neuroimaging, Centre for Neuroimaging Sciences, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Gispert JD; Barcelonaβeta Brain Research Center (BBRC), Pasqual Maragall Foundation, Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain.; Universitat Pompeu Fabra, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Madrid, Spain.
Corporate Authors: ALFA study†, BioFINDER, ADNI
Source: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2022 Jul; Vol. 18 (7), pp. 1383-1395. Date of Electronic Publication: 2021 Dec 08.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: John Wiley & Sons, Ltd Country of Publication: United States NLM ID: 101231978 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-5279 (Electronic) Linking ISSN: 15525260 NLM ISO Abbreviation: Alzheimers Dement Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1552-5279
DOI:10.1002/alz.12487